Protein
NAD-dependent protein deacylase 4
Organism
Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)
Function
NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.
Similarity
Belongs to the sirtuin family. Class III subfamily.
Sequence
MRLPAEALKDARKIVCFSGAGISAESGILTYLDQMPKLWAPYDPRALETANAFRESPALVWGWYLWRRRQVDRAQPNAAHLVWPQMVNLGYEVSVVTQNVDDLHERAGSTDVIHLHGSLTMPKCFACHRPAELTSDQMEIPDEGALVEPPRCKRCRGKLRPGVVWYGEDLPPGTWKNAVSLVKNCDALISVGTSGVVTPAADLPHIALASGATVIHVNTVDVGAQAANELMLVGRATDVLAKIHESLSTGKNNDNG