Protein
Communesin biosynthesis cluster-specific transcription factor cnsN
Organism
Penicillium expansum
Function
Transcriptional regulator; part of the gene cluster that mediates the biosynthesis of communesins, a prominent class of indole alkaloids with great potential as pharmaceuticals.
Sequence
MRPLPTGIYTPLPCFFHENEDIDIEALQSHVKFIASAGTIPVVSGSMGEAIHLNREEKKTIIRSARVALDEVNLHDVPIVAGAGGASTRESIELCKDAAEAGADYVMVIPPGYYAGALLADTSSIKKFFVDIAEASPLPVIIYNFPAVSGGIDMDSDLIVQIIQSSANICGVKLTCANVGKLTRIMAQVSRPEFQAAFPRSSATPFRAIDGFIDFLLPSISVGSAGAISGLPNIAPKSCVKLWNLCQDSGSSKQATELQNLIALADGVALKIGIAGMKKLLHRHFGRKVACDMPNGPPCLRCTNKYQECTFEEGPGPRKRARLCEQTETFGTCEQPDGWQDLLTETRPNIGQSEDLEAVSPQGSLLGANQELESTSPRTSHSSLSQDDTASLHSRSSLSSSPGRFPPSQKLVATSDSPSQINSLEFIPDAFSFYIGPTGVTDIHILSHQKYNDQNVSLPKVNGLKYRIMDNPGQKEMATVDFSPPTVFGITDHSLLEKAEPKLDPQLTENGWPRLWAMMDPTAAWHLIKLYSRYIDPYFPILSSHQIPSSSAELNKMPLALLTAICATALPFVMYDDSLYTMLLNPPSSEELYRLCWLCISQELHAPSLATLQACLLLQQRLPTNMYLSDTAFAWTLMATSLAVAQTIGLHRDTGSWTSIPAWEKRLRRRLWWGLYAMEKWVALARGMPSHLGDDDYDVSMLKADDIQDTLSDSPDTQSHIYHLSNLSTILSDIQRSFYSVKAIGKTSNDLQYSLDLARPMRVRLKDWRDNLPSNLRPVSNAVISGEDLDGNGSLYLSYIVTHVALLRALLRPLDRWPAIIKVNKEEPEATYEGAKAVVTGALLCVKEFVEFVERLTGAQWNAFWHSWSRPNFAIAGSFMVHLLQIVTPPNQTDSQSMPELLKYSFEKEHTELQDWIRRWRWATRISANGAAGVKGLTNLGFIKVETLIGNGT