Protein
Aminodeoxychorismate synthase
Organism
Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
Function
Involved in chloramphenicol biosynthesis (PubMed:8704974). Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine (By similarity).
Similarity
In the C-terminal section; belongs to the anthranilate synthase component I family.
Sequence
MRTLLIDNYDSFTHNLFQYIGEATGQPPVVVPNDADWSRLPLEDFDAIVVSPGPGSPDRERDFGISRRAITDSGLPVLGVCLGHQGIAQLFGGTVGLAPEPMHGRVSEVRHTGEDVFRGLPSPFTAVRYHSLAATDLPDELEPLAWSDDGVVMGLRHREKPLWGVQFHPESIGSDFGREIMANFRDLALAHHRARRDAADSPYELHVRRVDVLPDAEEVRRGCLPGEGATFWLDSSSVLEGASRFSFLGDDRGPLAEYLTYRVADGVVSVRGSDGTTTRTRRPFFSYLEEQLERRRVPVAPDLPFEFNLGYVGYLGYELKAETTGDPAHRSPHPDAAFLFADRAIALDHQEGCCYLLALDRRGHDDGARAWLRETAETLTGLAVRVPAEPTPAMVFGVPEAAAGFGPLARARHDKDAYLKRIDECLKEIRNGESYEICLTNMVTAPTEATALPLYSALRAISPVPYGALLEFPELSVLSASPERFLTIGADGGVESKPIKGTRPRGGTAEEDERLRADLAGREKDRAENLMIVDLVRNDLNSVCAIGSVHVPRLFEVETYAPVHQLVSTIRGRLRPGTSTAACVRAAFPGGSMTGAPKKRTMEIIDRLEEGPRGVYSGALGWFALSGAADLSIVIRTIVLADGRAEFGVGGAIVSLSDQEEEFTETVVKARAMVTALDGSAVAGAR