citT

Gene

citT

Protein

Citrate/succinate antiporter

Organism

Escherichia coli O157:H7

Length

487 amino acids

Function

Responsible for the uptake of citrate in exchange to the efflux of succinate. Has a relatively broad specificity for C(4)-dicarboxylates and tricarboxylates (By similarity).

Similarity

Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.

Mass

53.093 kDa

Sequence

MSLAKDNIWKLLAPLVVMGVMFLIPVPDGMPPQAWHYFAVFVAMIVGMILEPIPATAISFIAVTICVIGSNYLLFDAKELADPAFNAQKQALKWGLAGFSSTTVWLVFGAFIFALGYEVSGLGRRIALFLVKFMGKRTLTLGYAIVIIDILLAPFTPSNTARTGGTVFPVIKNLPPLFKSFPNDPSARRIGGYLMWMMVISTSLSSSMFVTGAAPNVLGLEFVSKIAGIQISWLQWFLCFLPVGVILLIIAPWLSYVLYKPEITHSEEVATWAGDELKTMGALTRREWTLIGLVLLSLGLWVFGSEVINATAVGLLAVSLMLALHVVPWKDITRYNSAWNTLVNLATLVVMANGLTRSGFIDWFAGTMSTHLEGFSPNATVIVLVLVFYFAHYLFASLSAHTATMLPVILAVGKGIPGVPMEQLCILLVLSIGIMGCLTPYATGPGVIIYGCGYVKSKDYWRLGAIFGVIYISMLLLVGWPILAMWN

Protein

Citrate/succinate antiporter: citT

Gene

citT

Protein

Citrate/succinate antiporter

Organism

Escherichia coli (strain K12)

Length

487 amino acids

Function

Responsible for the uptake of citrate in exchange with the efflux of succinate, fumarate or tartrate. Has a relatively broad specificity for C(4)-dicarboxylates and tricarboxylates (PubMed:9696764).

Similarity

Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.

Mass

53.093 kDa

Sequence

Protein

Citrate/succinate antiporter: citT

Gene

citT

Protein

Transcriptional regulatory protein CitT

Organism

Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)

Length

230 amino acids

Function

Member of the two-component regulatory system CitT/CitS.

Mass

26.482 kDa

Sequence

MTKLYKVLIIEDDFRVAQIQEQMVNDHPYFHVISTCRTGGEALDYLSEKAAALDLILLDVYIPDVKGLELLWAIREKFRDVDIMMVTAAKEVDTVQEALRGGIIDYLLKPVQKEVLHQRLDAYVQKRELFGERRQVSQEELDQLRQVQVRVQVGETPLPKGIDRLTLEKVVNALEEAETQGLTAMEGARLIGASRSTVRRYFEYLIHTKKAKAEVNYGDVGRPERRYFLC

Protein

Transcriptional regulatory protein CitT: citT

Gene

citT

Protein

Transcriptional regulatory protein CitT

Organism

Bacillus subtilis (strain 168)

Length

226 amino acids

Function

Member of the two-component regulatory system CitT/CitS. Regulates the expression of the citM-yflN operon. Phosphorylated CitT binds to the citM promoter to activate the transcription of the citM-yflN operon.

Mass

25.41 kDa

Sequence

MIHIAIAEDDFRVAQIHERLIKQLDGFKIIGKAANAKETLALLKEHKADLLLLDIYMPDELGTALIPDIRSRFPEVDIMIITAATETRHLQEALRAGIAHYLIKPVTADKFRQVLLQYKEKRKLLMSQPEVSQSMIDHIFGNGVKTALPAEDLPTGINSITLRKIKEALQTASEGLTAEELGEKMGASRTTARRYAEYLVSKEEARAELEYGIIGRPERKYYLAAD

Protein

Transcriptional regulatory protein CitT: citT