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cisd2-b

Gene
cisd2-b
Protein
CDGSH iron-sulfur domain-containing protein 2B
Organism
Xenopus laevis
Length
135 amino acids
Function
Regulator of autophagy that contributes to antagonize becn1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of bcl2 with becn1 and is required for bcl2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy (By similarity).
Similarity
Belongs to the CISD protein family. CISD2 subfamily.
Mass
15.442 kDa
Sequence
MMLESLARVFKVQLPAYLKRLPIPDSIAGFIRLTVLEWLRLLPFLGVLALLGYLAIRPFLPKKKQQKDSLINLKIQKENPKVVNEINIEDLHLAKAAYCRCWRSKTFPVCDGSHNKHNELTGDNVGPLILKKKEV