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cirbp-a

Gene
cirbp-a
Protein
Cold-inducible RNA-binding protein A
Organism
Xenopus laevis
Length
166 amino acids
Function
Cold-inducible mRNA binding protein. Acts cooperatively with elavl1/elrA to stabilize AU-rich sequence (ARE)-containing mRNAs by binding to them and inhibiting their deadenylation (By similarity). Essential for embryonic gastrulation and neural development, acting to maintain the expression of a set of adhesion molecules and cell movement during embryogenesis. Plays a role in the specification and migration of pronephros cells during embryonic kidney development.
Mass
17.903 kDa
Sequence
MSDEGKLFIGGLNFETNEDCLEQAFTKYGRISEVVVVKDRETKRSRGFGFVTFENVDDAKDAMMAMNGKSVDGRQIRVDQAGKSSGERRGGYRGGSSGGRGFFRGGRGRGGGDRGYGSSRFDNRSGGYGGSSGSRDYYGSGRSQGSYGDRSGGSYRDSYDSYATHE