About Products Protein Database Contact

cimA

Gene
cimA
Protein
(R)-citramalate synthase
Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Length
547 amino acids
Function
Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate.
Similarity
Belongs to the alpha-IPM synthase/homocitrate synthase family.
Mass
59.82 kDa
Sequence
MATKKTSLWLYDTTLRDGAQREGISLSLTDKLTIARRLDQLGIPFIEGGWPGANPKDVQFFWQLQEEPLEQAEIVAFCSTRRPHKAVETDKMLQAILSAGTRWVTIFGKSWDLHVLEGLQTSLAENLAMISDTIAYLRSQGRRVIYDAEHWFDGYRANPDYALATLATAQQAGAEWLVMCDTNGGTLPGQISEITTKVRRSLGLDGQSDRQPQLGIHAHNDSGTAVANSLLAVEAGATMVQGTINGYGERCGNANLCTLIPNLQLKLDYDCIEPEKLAHLTSTSRLISEIVNLAPDDHAPFVGRSAFAHKGGIHVSAVQRNPFTYEHIAPNLVGNERRIVVSEQAGLSNVLSKAELFGIALDRQNPACRTILATLKDLEQQGYQFEAAEASFELLMRQAMGDRQPLFLVQGFQVHCDLLTPAENPAYRNALATVKVTVNGQNILEVAEGNGPVSALDQALRKALTRFYPQIADFHLTDYKVRILDGGAGTSAKTRVLVESSNGDRRWTTVGVSGNILEASYQAVVEGIEYGLRLLTCGLTNQEAISS
Protein
(R)-citramalate synthase: cimA

Gene
cimA
Protein
(R)-citramalate synthase
Organism
Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Length
538 amino acids
Function
Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate.
Similarity
Belongs to the alpha-IPM synthase/homocitrate synthase family.
Mass
60.29 kDa
Sequence
MSIKVYDTTLRDGAQAFGVSFSLEDKIRIAEALDDLGVHYLEGGWPGSNPKDIAFFEAVKGMNFKNLKVAAFSSTRRPDVKIEEDANIQTLIKAETPVYTIFGKSWDLHVEKALRTTLEENLKMIYDTVSYLKRFADEVIYDAEHFFDGYKANREYALKTLKVAEEAGADCLVLADTNGGTLPHEIEEIIEDVKKHVKAPLGIHAHNDSDVAVANTLAAVRKGAVHVQGTINGLGERCGNANLCSVIPNLVLKMGLEVIPKENLKKLFDVAHLVAELSGRPHIENMPYVGDYAFAHKGGVHVSAIKRDPRTYEHIDPELVGNRRIISISELSGKSNVLEKIKEMGFEIDESSPKVREILKKIKELEAQGYHFEGAEASFELLVRDMLGKRKKYFEFLGFTVMTIKNRDEESFSEATVKVRVPDEVAKRLGHDEPFEHTAAEGEGPVEALDRAVRKALEKFYPSLKDTKLTDYKVRILNEQAGTKATTRVLIESSDGKRRWGTVGVSPNIIEASWTALLESLEYKLHKDEEEMRNDEEN
Protein
(R)-citramalate synthase: cimA

Gene
cimA
Protein
(R)-citramalate synthase
Organism
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Length
534 amino acids
Function
Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate.
Similarity
Belongs to the alpha-IPM synthase/homocitrate synthase family.
Mass
57.527 kDa
Sequence
MTATSELDDSFHVFDTTLRDGAQREGINLTVADKLAIARHLDDFGVGFIEGGWPGANPRDTEFFARARQEIDFKHAQLVAFGSTRRAGANAAEDHQVKALLDSGAQVITLVAKSHDRHVELALRTTLDENLAMVADTVSHLKAQGRRVFVDCEHFFDGYRANPEYAKSVVRTASEAGADVVVLCDTNGGMLPAQIQAVVATVLADTGARLGIHAQDDTGCAVANTLAAVDAGATHVQCTANGYGERVGNANLFPVVAALELKYGKQVLPEGRLREMTRISHAIAEVVNLTPSTHQPYVGVSAFAHKAGLHASAIKVDPDLYQHIDPELVGNTMRMLVSDMAGRASIELKGKELGIDLGGDRELVGRVVERVKERELAGYTYEAADASFELLLRAEAEGRPLKYFEVESWRAITEDRPDGSHANEATVKLWAKGERIVATAEGNGPVNALDRSLRVALEKIYPELAKLDLVDYKVRILEGVHGTQSTTRVLISTSDGTGEWATVGVAENVIAASWQALEDAYTYGLLRAGVAPAE
Protein
(R)-citramalate synthase: cimA

Gene
cimA
Protein
(R)-citramalate synthase
Organism
Aquifex aeolicus (strain VF5)
Length
528 amino acids
Function
Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate.
Similarity
Belongs to the alpha-IPM synthase/homocitrate synthase family.
Mass
59.215 kDa
Sequence
MAEKVYIYDTTLRDGSQMEGVSFSLEDKIRIAEKLDDFGIHYIEGGWPYANPKDNLFFQKAKKMNFKNAKLTAFGSTRRPNKKVSEDPQVESLIKAETPVVTIFGKSWDLHVTDALKTTLEENLNMIYETVEYLKRYVDEVIFDAEHFFDGYKSNPEYALQVLEAALKGGADWVVLCDTNGGTLPHEIYEITKKVKERFKDANVGIHAHNDSETAVANSLMAVLAGARQVHGTINGIGERTGNANLCSIIPNLQLKLGFDVIPQENLKKLTELANFVAEIINMPLPRNMPYVGESAFAHKGGVHASAVLKNAKTYEHINPELVGNKRKITVSDLAGRSNLVHKLKEFGIEIDPKSPELKKLIDKIKELEKEGYHFEAAEASLELLIKRHFGLVKDYFDFDAYRVLIAKRRDDSLPTSEATVRLSVEGVEEHTASLGNGPISALDRALRKALEEFYPNLKELQLIDYKVRIINESAGTSAKVRVLIESTDGKRKWGTVGVSENVIEASWIALRDSIVYKLMKDEEEGIL
Protein
(R)-citramalate synthase: cimA

Gene
cimA
Protein
(R)-citramalate synthase
Organism
Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA)
Length
528 amino acids
Function
Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate. Makes part of the main pathway for isoleucine biosynthesis in G.sulfurreducens, i.e. the citramalate-dependent pathway.
Similarity
Belongs to the alpha-IPM synthase/homocitrate synthase family.
Mass
59.071 kDa
Sequence
MSLVKLYDTTLRDGTQAEDISFLVEDKIRIAHKLDEIGIHYIEGGWPGSNPKDVAFFKDIKKEKLSQAKIAAFGSTRRAKVTPDKDHNLKTLIQAEPDVCTIFGKTWDFHVHEALRISLEENLELIFDSLEYLKANVPEVFYDAEHFFDGYKANPDYAIKTLKAAQDAKADCIVLCDTNGGTMPFELVEIIREVRKHITAPLGIHTHNDSECAVANSLHAVSEGIVQVQGTINGFGERCGNANLCSIIPALKLKMKRECIGDDQLRKLRDLSRFVYELANLSPNKHQAYVGNSAFAHKGGVHVSAIQRHPETYEHLRPELVGNMTRVLVSDLSGRSNILAKAEEFNIKMDSKDPVTLEILENIKEMENRGYQFEGAEASFELLMKRALGTHRKFFSVIGFRVIDEKRHEDQKPLSEATIMVKVGGKIEHTAAEGNGPVNALDNALRKALEKFYPRLKEVKLLDYKVRVLPAGQGTASSIRVLIESGDKESRWGTVGVSENIVDASYQALLDSVEYKLHKSEEIEGSKK
Protein
(R)-citramalate synthase: cimA

Gene
cimA
Protein
Putative (R)-citramalate synthase CimA
Organism
Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)
Length
509 amino acids
Function
Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate.
Similarity
Belongs to the alpha-IPM synthase/homocitrate synthase family.
Mass
55.687 kDa
Sequence
MREANADADPPDEVRIFDTTLRDGEQTPGVALTPEEKLRIARKLDEIGVDTIEAGFAAASEGELKAIRRIAREELDAEVCSMARMVKGDVDAAVEAEADAVHIVVPTSEVHVKKKLRMDREEVLERAREVVEYARDHGLTVEISTEDGTRTELEYLYEVFDACLEAGAERLGYNDTVGVMAPEGMFLAVKKLRERVGEDVILSVHCHDDFGMATANTVAAVRAGARQVHVTVNGIGERAGNAALEEVVVVLEELYGVDTGIRTERLTELSKLVERLTGVRVPPNKAVVGENAFTHESGIHADGILKDESTYEPIPPEKVGHERRFVLGKHVGTSVIRKKLKQMGVDVDDEQLLEILRRLKRLGDRGKRITEADLRAIAEDVLGRPAERDIEVEDFTTVTGKRTIPTASIVVKIDGTRKEAASTGVGPVDATIKALERALKDQGIDFELVEYRAEALTGGTDAITHVDVKLRDPETGDIVHSGSSREDIVVASLEAFIDGINSLMARKRS
Protein
Putative (R)-citramalate synthase CimA: cimA

Gene
cimA
Protein
Putative (R)-citramalate synthase CimA
Organism
Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1)
Length
503 amino acids
Function
Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate.
Similarity
Belongs to the alpha-IPM synthase/homocitrate synthase family.
Mass
53.275 kDa
Sequence
MIVLFVEPIRFFDTTLRDGEQTPGVSLTPAGKLEIATHLADVGVHVIEAGSAAASVGERESIRAIADAGLAAECCTYVRALPGDIDLAADAGADSVHLVVPVSDLHIAKKLRKTREQVSEMAWSAVEYAKERGLVVELSGEDASRADQDFLAEVFREGVERGADRLCFCDTVGLLTPERAAAIIPPLLFAPLSIHCHDDLGFGLATTVAALRAGATCAHVTVNGLGERAGNTSLEELVMALEVLYGVDTGIATEELYPLSTHVARLTGVPLATNKPIVGEMAFTHESGIHAHGVMRDASTYEPLQPERVGRRRRIVLGKHSGSAAVEAALHDMGYAPSAAQLKEIVDRIKRLGDAGMRITDADIMAIADTVMEIEFTPCIELRQFTIVSGSNAIPTASVTMLVRGEEITGAAVGTGPVDAAIRALQRSVADVGSVRLDEYSVDAITGGTDALVDVSVKLSKDGKTVTSRGARTDIIMASVEAVIAGMNRLLREEHEDRSQDSD
Protein
Putative (R)-citramalate synthase CimA: cimA

Gene
cimA
Protein
Putative (R)-citramalate synthase CimA
Organism
Methanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c)
Length
500 amino acids
Function
Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate.
Similarity
Belongs to the alpha-IPM synthase/homocitrate synthase family.
Mass
52.466 kDa
Sequence
MIALFGEKLRFFDTTLRDGEQTPGVSLTPDQKCIIATALAAVGVDVIEAGSAAASPGDRAAIRQIANAGLGVEVCTFVRAMTGDIDAAVECGVDSVHLVVPVSDLHIQKKLRKDRATVAAMANKAVDYAKERGLIVELSGEDASRADQSFLAEVFASGVEHGADRLCFCDTVGLMTPERTALMIPPLAAIAPLSIHCHDDLGFGLATTIAALKAGASCAHVTVNGLGERAGNTPLEEVVMALERLYGYDTRIRTERLYPLSVLVSRLTGVPLPAQKPIVGELAFTHESGIHADGILKDPSTYEPLAPETVGRTRRIILGKHSGSASVEAALQESGYRPTPAQLQVIVARVKHLGDQGHRVTDGDLAAIAEAVLEVSTEPVLVLKQFTVVSGSGVLPTASVTLLVNGAEVTNAATGTGPVDAAIEALRRSVADVAAISLLEYHVDAITGGTDALVEVTATLSNGEMTRTSRGAETDIIAASVEAVVQGMNRLLRRRDEDRR
Protein
Putative (R)-citramalate synthase CimA: cimA

Gene
cimA
Protein
Putative (R)-citramalate synthase CimA
Organism
Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)
Length
496 amino acids
Function
Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate.
Similarity
Belongs to the alpha-IPM synthase/homocitrate synthase family.
Mass
53.705 kDa
Sequence
MQVRVLDTTLRDGEQTPGVSLTPEEKLRIALKIDALGADIIEAGSAITSEGEREGIRKITSEGLRAEICSFARAVREDIDAAISCDVDSVHLVVPTSDLHLEHKLRKTREEVLEQAVDCTEYAVDHGILVELSAEDSTRSDMDFLRTIFREGIEAGAERICACDTVGILTPERSYEFYRGLSELGAPLSVHCHNDFGLAVANSLAGLRAGASEVHATINGIGERAGNAALEEVVVALKSLYDVDTSINIEMLYETSRMVARMTGVYLQPNKAIVGENAFAHESGIHADGVLKKAETYEPITPEMVGHGRGFVMGKHIGTHALRKRLDELGMKVADDKLMEIFRRVKTLGDMGKCVTDVDLQAIAEDVLGVMEDKVVDLQEVTIVSGNRVTPTASVKLRVDDREVLEAGTGVGPVDAAIVAIKKSLEDFADITLEEYHVDAITGGTDALIDVVIKLRHGDRIISARSTQPDIIMASVEAFLSGVNRLLANEKSEGTH
Protein
Putative (R)-citramalate synthase CimA: cimA

Gene
cimA
Protein
(R)-citramalate synthase CimA
Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
Length
491 amino acids
Function
Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate.
Similarity
Belongs to the alpha-IPM synthase/homocitrate synthase family.
Mass
53.493 kDa
Sequence
MMVRIFDTTLRDGEQTPGVSLTPNDKLEIAKKLDELGVDVIEAGSAITSKGEREGIKLITKEGLNAEICSFVRALPVDIDAALECDVDSVHLVVPTSPIHMKYKLRKTEDEVLETALKAVEYAKEHGLIVELSAEDATRSDVNFLIKLFNEGEKVGADRVCVCDTVGVLTPQKSQELFKKITENVNLPVSVHCHNDFGMATANTCSAVLGGAVQCHVTVNGIGERAGNASLEEVVAALKILYGYDTKIKMEKLYEVSRIVSRLMKLPVPPNKAIVGDNAFAHEAGIHVDGLIKNTETYEPIKPEMVGNRRRIILGKHSGRKALKYKLDLMGINVSDEQLNKIYERVKEFGDLGKYISDADLLAIVREVTGKLVEEKIKLDELTVVSGNKITPIASVKLHYKGEDITLIETAYGVGPVDAAINAVRKAISGVADIKLVEYRVEAIGGGTDALIEVVVKLRKGTEIVEVRKSDADIIRASVDAVMEGINMLLN
Protein
(R)-citramalate synthase CimA: cimA

Gene
cimA
Protein
Putative (R)-citramalate synthase CimA
Organism
Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Length
489 amino acids
Function
Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate.
Similarity
Belongs to the alpha-IPM synthase/homocitrate synthase family.
Mass
53.346 kDa
Sequence
MQVKILDTTLRDGEQTPGVSLSVEQKVMIAEALDNLGVDIIEAGTAIASEGDFQAIKEISQRGLNAEICSFARIKREDIDAAADAGAESIFMVAPSSDIHINAKFPGKDRDYVIEKSVEAIEYAKERGLIVEFGAEDASRADLDFVIQLFKRAEEAKADRITFADTVGVLSPEKMEEIVRKIKAKVKLPLAIHCHDDFGLATANTIFGIKAGAEEFHGTINGLGERAGNAAIEEVVIALEYLYGIKTKIKKERLYNTSKLVEKLSRVVVPPNKPIVGDNAFTHESGIHTSALFRDAKSYEPISPEVVGRKRVIVLGKHAGRASVEAIMNELGYKATPEQMKEILARIKEIGDKGKRVTDADVRTIIETVLQIKREKKVKLEDLAIFSGKNVMPMASVKLKIDGQERIEAAVGLGPVDAAINAIRRAIKEFADIKLVSYHVDAITGGTDALVDVVVQLKKDNKIVTARGARTDIIMASVEAFIEGINMLF
Protein
Putative (R)-citramalate synthase CimA: cimA

Gene
cimA
Protein
Putative (R)-citramalate synthase CimA
Organism
Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)
Length
483 amino acids
Function
Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate.
Similarity
Belongs to the alpha-IPM synthase/homocitrate synthase family.
Mass
52.274 kDa
Sequence
MRDGEQTPGVALTREKKLLIARALDEMRINVIEAGSAITSAGERESIKAVANAGLDAEICSYCRIVKMDVDHALECDVDSIHLVAPVSDLHIKTKIKKDRDTVRQIAAEVTEYAKDHGLIVELSGEDASRADPEFLKAIYSDGIDAGADRLCFCDTVGLLVPEKTTEIFRDLSSSLKAPISIHCHNDFGLATANTVAALAAGAKQSHVTINGLGERAGNASLEEVVMSLEWLYKYDTGIKHEQIYRTSRLVSRLTGIPVSPNKALVGGNAFTHEAGIHVHGLLADKSTYEPMSPEYIGRQRQIVLGKHAGRSSITLALKEMGLEADEAQTEEIFNRVKQMGDQGKHITDADLQTIAETVLDIYKEPIVKLEEFTIVSGNRVTPTASIKLNVKDKEIVQAGIGNGPVDAVINAIRRAVSSCAEDVVLEEYHVDSITGGTDALVEVRVKLSKNGKVITASGARTDIIMASVEAVMNGMNRLIREE
Protein
Putative (R)-citramalate synthase CimA: cimA

Gene
cimA
Protein
Putative (R)-citramalate synthase CimA
Organism
Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)
Length
483 amino acids
Function
Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate.
Similarity
Belongs to the alpha-IPM synthase/homocitrate synthase family.
Mass
52.04 kDa
Sequence
MRDGEQTPGVALTKEKKLLIARALDEMKINVIEAGSAITSAGERESVRAVANAGLSAEICSYCRIVKTDVDHALECDVDSIHLVVPVSDLHIRTKIKKDRDTVRQIAADVTEYAKEHGLIVELSGEDSSRADLGFLKAVYSDGIDAGADRLCFCDTVGLLVPEKTTEIFRDLSSSLKAPISIHCHNDFGLATANTVAALAAGAKQAHVTINGLGERAGNASLEEVVMCLEWLYKYDTGIKHEQIYRTSRLVSRLTGIPVSPNKALVGGNAFTHEAGIHVHGLLADKATYEPMSPEYIGRQRQIVLGKHAGRSSITLALKEMGLEADDAQTEEIFNRVKQMGDQGKHVTDADLQIIAETVLDIYKEPLVKLEEFTIVSGNRVTPTASIKLNVKDKEIVQAGIGNGPVDAVINAIRRAVSSCAEDVILEEYHVDAVTGGTDALVEVRVKLSKEGKSITASGARTDIIMASVEAVMNGLNRLVRAE
Protein
Putative (R)-citramalate synthase CimA: cimA