ceh-24

Homeobox protein ceh-24

299 amino acids

Probable transcriptional regulator that is required in neural development for the normal formation of sublateral cholinergic motor neuron processes. Plays a role in regulating the expression of acetylcholine transporter protein unc-17 in the sublateral processes. In particular, it is required in sublateral motor neurons for a left-right turning behavior that occurs during the lethargus phase of the normal sleep process called flipping. During flipping animals rotate 180 degrees about their longitudinal axis.

Belongs to the NK-2 homeobox family.

33.077 kDa

MSEKETPSPVLDVKKEKNEETGIDEEKSSEDDCSKRSKVKSNPSKFSVNSILSPLESLVRVQQQLLKMAASKSGTPGTNAGVPGAFPYGPGRLPGNYFAGPFPGYSGAQPNWYNGNDPRFAAAAALLPCSIDPVRSAINHQFSMSSMSQRRKRRVLFSQAQVYELERRFKQAKYLTAPEREQLANSIRLTPTQVKIWFQNHRYKCKRQEKEKAMSGLGHSEDGSSPPPDNDDDDDKYSIEMDDKDDEEEEESEKPVLKPSGVFGLPYPPNAAAAAAAAAAAFNFPFAAQGPNPAYYMRW

ceh-24

Homeobox protein ceh-24

293 amino acids

Probable transcriptional regulator that is required in neural development for the normal formation of sublateral cholinergic motor neuron processes. Plays a role in regulating the expression of acetylcholine transporter protein unc-17 in the sublateral processes. In particular, it is required in sublateral motor neurons for a left-right turning behavior that occurs during the lethargus phase of the normal sleep process called flipping. During flipping animals rotate 180 degrees about their longitudinal axis.

Belongs to the NK-2 homeobox family.

32.371 kDa

MSEKESPSPQHKKDEVVDDTEQETKDSEDDATKKMKIKEGSKFTMNSILSPLESLARVQQQLLKMAAAQSGFGGNGSGGNGANGFPYPARFATNCFSGPFPGYNGSQNWYNGNDARFAAAAALLPCAIDPVRSAINHQFSMSQRRKRRVLFSQAQVYELERRFKQAKYLTAPEREQLANSIRLTPTQVKIWFQNHRYKCKRQEKEKAMSGLGHGDDGCSPPPGDDDDDDDKYSIEMDDKDDEEEDGAKPMLKSNGVFGLPYPSPANAAAAAAAAAFNFQFGAQGPNPAYFMRW