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ccq1

Gene
ccq1
Protein
Coiled-coil quantitatively-enriched protein 1
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Length
735 amino acids
Function
Component of the meiotic bouquet that facilitates meiotic nuclear reorganization of the telomeres to the centrosome. Links telomeres to the meiotic centrosome component pcp1. Essential for the formation of normal telomere clusters during meiotic prophase. Required for telomere length regulation and chromosome segregation. Required for proper positioning of nucleosomes at heterochromatic loci and for transcriptional gene silencing (TGS) function of the Snf2/Hdac-containing repressor complex (SHREC).
Mass
83.301 kDa
Sequence
MSEINDFTNSIIINESDTKYEVYSEVNSSNRWIAKEDCPSPLEDVWLLKLAGHKRKLEEPLSCMRNEEPASKQREIEKFLRTDLDHSENDFLTQEVDEFPSTQQLFPIPLQNDTAFDSSEESITKSSKSSFSVLDIGLPMSALQRKMMHRLVQYFAFCIDHFCTGPSDSRIQEKIRLFIQSAHNIAKHPSLYDTEVRNPSAAESTNSHVSLDASNFSSYAENSSKFLFLQELFKNLSPSYSKTFFLFISNQFLANTLTQWLKSQNIDAELWAEEDAKTSQHPAIWICVSKKAPSASHFLQSCPDLSATIFYDIEAYMSVTSSLPSIQSLVLRLIHLGSIEHAIKCFQSSYNASFLVNIVGVVATLSSSSEENSEASNLSTLFEKSGNFEEILGSESHSSITEKTRDIAKNVATWLKNGENFSSWPLPPLMDLASLSVAEPRDSQPSVSQVNDTFVKSSDSTFPSSQSMQSPSKLHSLTSNATDLLSSSSLKKNFFSQQEADEVELSNNYDLQGAAVQYLQRRLRMVEDELHEAINSKNVQQSRSEELEQQISKLTDNLQEYRNTVRELKLDLEKSKKKNEDLSKLEVEKVEEIANLKKELTHLAKQQEFGFKYVQEFSNEDLQGKLIEANEKNYKLTQLLKTQKEDADFITNQYQNASTFAAEQSKEVAKLQAECKRLQAINSKVMEEVKVYNDSRVEALLAKVSSLEETLKILEQKSLPKFTPHNQSPRIIDSN