Protein
CCR4-NOT transcription complex subunit 7
Organism
Caenorhabditis elegans
Function
Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression.
Similarity
Belongs to the CAF1 family.
Sequence
MASSSSGGAGGAGGASGAPEVKIHNVYMSNVEEEFARIRGFVEDYPYVAMDTEFPGVVATPLGTFRSKEDFNYQQVFCNVNMLKLIQVGFAMVNDKGELPPTGDVWQFNFNFSFAEDMFSHESVEMLRQAGIDFTLLQNNGIPTAVFGELLTTSGLITDPRITWLTFSSGYDFGYLLKSITLGDLPKEESTFFMCHKTLFPTSFDIKILLRTPNCASAKLKGGLQEVADQLDVKRQGVRHQAGSDALLTAATFFKIKKQFFGDNWNQIAPLICGHMFGLGSSLSLFHSSGSTSRLGDETPQGLIGVPQQA