Protein
CRISPR-associated protein Cas1 3
Organism
Methanobrevibacter ruminantium (strain ATCC 35063 / DSM 1093 / JCM 13430 / OCM 146 / M1)
Function
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
Similarity
Belongs to the CRISPR-associated endonuclease Cas1 family.
Sequence
MKILIEGYNKSIHKRDNQILIMEKEGELEKINIKKIDDITIIGKGSITFDALRLISENNVRLMSIDYFGKINYTLEYPSNENIFLRKQQYKTSENHKGLIIAREMIMSKMINQKSTIKTLNKNKKLENVKIFERNINEAIKQIGSLRFGERTDIEKSKMKMMGIEGSASVDYWLAVNELLPKEIGFFSRNNRHPNDITNASLNYAYAILASEVNKALVINGLDSYCGFLHFDRQKRTSLTFDLMEEFRQQLVDKVVFSLVNTKQISNDDLDKRNNSISLDVRKLIIGRVLDKVNSNINYEGENLSYAQIIDKQAKKIVNYLINGEKYTGFSLRW