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carH

Gene
carH
Protein
HTH-type transcriptional repressor CarH
Organism
Myxococcus xanthus
Length
299 amino acids
Function
Negative regulator of the carB operon in the dark. Binds specifically to the CarA operator, in the region around the carB promoter, which blocks access to the RNA polymerase.
Similarity
Belongs to the CarA/CarH B12-binding photoregulator family.
Mass
32.929 kDa
Sequence
MAERTYRINIAAELAGVRVELIRAWERRYGVLTPRRTPAGYRAYTDRDVAVLKQLKRLTDEGVAISEAAKLLPQLMEGLEAEVAGRGASQDARPHAETWRESMLAATQAYDQPRVSDVLDEVLAALPPLKAFDEVLAPLLCDVGERWESGTLTVAQEHLVSQMVRARLVSLLHAAPLGRHRHGVLACFPEEEHEMGLLGAALRLRHLGVRVTLLGQRVPAEDLGRAVLALRPDFVGLSTVASRSAEDFEDTLTRLRQALPRGLPVWVGGAAARSHQAVCERLAVHVFQGEEDWDRLAGT

Gene
carH
Protein
HTH-type transcriptional repressor CarH
Organism
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Length
285 amino acids
Function
Negative regulator of genes involved in carotenoid biosynthesis.
Similarity
Belongs to the CarA/CarH B12-binding photoregulator family.
Mass
31.139 kDa
Sequence
MTSSGVYTIAEVEAMTGLSAEVLRQWERRYGFPKPRRTPGGHRLYSAEDVEALKTIKRWLEEGATPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGTVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLPRGPEKEAI