Protein
HTH-type transcriptional repressor CarH
Organism
Myxococcus xanthus
Function
Negative regulator of the carB operon in the dark. Binds specifically to the CarA operator, in the region around the carB promoter, which blocks access to the RNA polymerase.
Similarity
Belongs to the CarA/CarH B12-binding photoregulator family.
Sequence
MAERTYRINIAAELAGVRVELIRAWERRYGVLTPRRTPAGYRAYTDRDVAVLKQLKRLTDEGVAISEAAKLLPQLMEGLEAEVAGRGASQDARPHAETWRESMLAATQAYDQPRVSDVLDEVLAALPPLKAFDEVLAPLLCDVGERWESGTLTVAQEHLVSQMVRARLVSLLHAAPLGRHRHGVLACFPEEEHEMGLLGAALRLRHLGVRVTLLGQRVPAEDLGRAVLALRPDFVGLSTVASRSAEDFEDTLTRLRQALPRGLPVWVGGAAARSHQAVCERLAVHVFQGEEDWDRLAGT