cactin

Cactin

835 amino acids

May be involved in the regulation of innate immune response (By similarity). Plays a role during early embryonic development. Involved in the formation of the anteroposterior axis with important roles also in neural development.

Belongs to the CACTIN family.

97.996 kDa

MGSKKHRRSRSRSRSRERARVVRHDRSPGDRHSRNRSPVKSSRRRARSDSGGSRSSGGSAGPSRQRGRESGHSSDSDRQHRNTHGRNRDSSSDDDYHDKKKQALKKKHNDEKDSRSRRRKSRSSSGSSTNSSRERNRSKTSRSRERERRRRQSRSSSRERHRDQRRRRNSPERDRDRRRRSQSRSSSSSSSDSDHGGKSTQGGSSSKEEKKKQRDLMKALETPEEKRARRLAKKEAKERKKREKMGWSEEYMGYTNADNPFGDNNLLGTFIWQKALEKKGIGHLSEKNLKDRNKHIQEENRRELQKVKQLRLEREREKAMREQELEMLQREKEAEHFKTWAEQEDNFHLHQAKLRSKIRIRDGRAKPIDLLAKYISAEDDDLSVEMHEPYTFLNGLTVTDMEDLLEDIKVYMELECGKNVDFWRDMTTITEDEISKLRKLEASGKGPGDRREGINTSVSTDVQSVFKGKTYSQLQALYMNIESKIQAGGSNLDIGYWESLLQQVRVYMARARLRERHQDVLRQKLYKLKQEQGVESEPLFPIIKEEPEKEQPISREAGSGEEEAGSSSQQADREEDEDRRSRRTGGEEAERSGRSSPEEEKKGEEEEGEKDEAPEAVLTEEDLIQQSQAEYDSGRYSPTLLQNSELPLDTHIIAEEEDLQRLLLARRQMQVTGDASESAEDLFVRRAKEGMGGDEAQFSVEMPLTGKMYLWADKYRPRKPRFFNRVHTGFEWNKYNQTHYDFDNPPPKIVQGYKFNIFYPDLIDKRSTPQYFLEPCPDNKDFGILRFHAGPPYEDIAFKIVNREWEYSHRHGFRCQFANGIFQLWFHFKRYRYRR

Cactin

Cactin

772 amino acids

Involved in the regulation of innate immune response. Acts as negative regulator of Toll-like receptor and interferon-regulatory factor (IRF) signaling pathways. Contributes to the regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous proinflammatory stimuli. May play a role during early embryonic development. Probably involved in pre-mRNA splicing (By similarity).

Belongs to the CACTIN family.

90.661 kDa

MRGAGRQMGRDSRSRSRSVGRRGRKQRSRSRGRSRSRSRSRSRSRSRSRSRSRSHGRSSRRRREHERRRERKRRSRGRRSDSEGEQRQKSRRRSQSLRPPRWHSQNQSSCSDSGEERAQGSWARKGHRRSWSPGSSASSLDSPRRSRSPGTATLALSQQQSLQERLRLREERKQQEELLKAFETPEEKRARRLAKKEAKERKKREKMGWGEEYMGYTNTDNPFGDNNLLGTFIWNKALEKKGISHLEEKELKERNKRIQEDNRLELQKVKQLRLEREREKAMREQELELLQREKEAEHFKTWEEQEDSFHLRQAKLRSKIRIRDGRAKPIDLLAKYISAEDDDLAVEMHEPYTFLNGLTVADMEDLLEDIQVYMELEQGKNVDFWRDMTTITEDEIAKLRKLEASGKGPGERREGVNASVSSDVQSVFKGKTYNQLQVIFQGIEGKIRAGGPNLDMGYWESLLQQLRAHMARARLRERHQDVLRQKLFKLKQEQGVESEPLFPILKSEPSAAHSPEPEERPPSPGTSVDPVEPVEPEEATAPGEAEGEAEGEAVLMEEDLIQQSLADYDAGRYSPRLLTAHELPLDAHVLEPHEDLQRLQLSRQQLQATGDASESAEDIFFRRAREGMGQDEAQFSVEMPLGGRAYLWADKYRPRKPRFFNRVHTGFEWNKYNQTHYDFDNPPPKIVQGYKFNIFYPDLIRKRATPEYFLEACADNRDFAILRFHAGPPYEDIAFKIVSREWEYSHRHGFRCQFANGIFQLWFHFKRYRYRR

CACTIN

Cactin

758 amino acids

Involved in the regulation of innate immune response. Acts as negative regulator of Toll-like receptor and interferon-regulatory factor (IRF) signaling pathways. Contributes to the regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous proinflammatory stimuli. May play a role during early embryonic development. Probably involved in pre-mRNA splicing.

Belongs to the CACTIN family.

88.702 kDa

MGRDTRSRSRSAGRRGRRRQSQSGSRSRSRSHGRRNRRRREDEGRRRRRRRSRERRSDSEEERWQRSGMRSRSPPRPKWHSRDGSSQSDSGEEQSRGQWARRRRRARSWSPSSSASSSASPGRSQSPRAAAAALSQQQSLQERLRLREERKQQEELMKAFETPEEKRARRLAKKEAKERKKREKMGWGEEYMGYTNTDNPFGDNNLLGTFIWNKALEKKGISHLEEKELKERNKRIQEDNRLELQKVKQLRLEREREKAMREQELEMLQREKEAEHFKTWEEQEDNFHLQQAKLRSKIRIRDGRAKPIDLLAKYISAEDDDLAVEMHEPYTFLNGLTVADMEDLLEDIQVYMELEQGKNADFWRDMTTITEDEISKLRKLEASGKGPGERREGVNASVSSDVQSVFKGKTYNQLQVIFQGIEGKIRAGGPNLDMGYWESLLQQLRAHMARARLRERHQDVLRQKLYKLKQEQGVESEPLFPILKQEPQSPSRSLEPEDAAPTPPGPSSEGGPAEAEVDGATPTEGDGDGDGEGEGEGEAVLMEEDLIQQSLDDYDAGRYSPRLLTAHELPLDAHVLEPDEDLQRLQLSRQQLQVTGDASESAEDIFFRRAKEGMGQDEAQFSVEMPLTGKAYLWADKYRPRKPRFFNRVHTGFEWNKYNQTHYDFDNPPPKIVQGYKFNIFYPDLIDKRSTPEYFLEACADNKDFAILRFHAGPPYEDIAFKIVNREWEYSHRHGFRCQFANGIFQLWFHFKRYRYRR

cactin

Cactin

720 amino acids

Plays a role during early embryonic development. Involved in the dorsal-ventral embryonic patterning. Probably acts as a negative regulator of the NF-kappa-B (Rel) signaling pathway.

Belongs to the CACTIN family.

86.556 kDa

MPKEKSKHRHRSRSRERRDHRSPDPRSSRNRDRDREREREKDRDHRDHRDKERDQRREREKDKSRDKKREHKSRRRRSSSSSSSPSSSTSSSVPGAPRSPLVKSPMKLLQTLEARRLVEQKDRQRKKEELKAHETPEEKRARRLREKQAKEQRRRERMGWDNEYQTYSNEDNPFGDSNLTSTFHWGKKLEVEGLSNLSTKTVEVLSLQKQLENRRELEKVKKRRQERELERQVREDDLMMQQRAKEAVQFREWQRQEDQFHLEQARLRSEIRIRDGRAKPIDLLAQYVAAGNEPLEECLEMQMHEPYVLLNGLPVEELEDLLVDIKVYEELEQGKHIDFWNDMITIVQDELQRQQKLEAENSSLNQRRDGIHQAVVKDVADIFRGKNAQQLEEMRHRIEAKISGRADGVDISYWESLLSQLKAHMARARLRDRHQALLREKLSLLKRENDNETLQEKVAPQVKEEEMETQDAEDPEVEEGSPEDEEDPLNELRKTVRLYQAGNYSPRYIREEDFTGRRAQNEDVDEPEAEGLLYEEEDDERRTQRQRLLILHPERVDNNQLTPQELRMRNEAKQGMQGDEAEFSVETTLDAVPQLATDKYRPRKPRYFNRVHTGFEWNKYNQTHYDMDNPPPKIVQGYKFNIFYPDLMDKSQTPQYFLTPCADNGDFAVLRFHTGPPYEDIAFKIVNREWEFSYKRGFRCQFHNNIFQLWFHFKRYRYRR

CACTIN

Cactin

688 amino acids

Involved in the regulation of G1 progression and stage differentiation of tachyzoites. May play a role in gene expression.

Belongs to the CACTIN family.

79.556 kDa

MGKKRRKHDGSGSSRSPSPDRIREARNPSQAEVAGFRAPPSGKPAMTVKQLREERQKLLHEHFGYSNTNNPFGDRLLAEPFVWKKKNQLLQAAGQKGKTTVAALIHSSKSKVQEIENVKRRREEREKEEELMQQQREELQREKEREHYEEYAQKEELFHRSNQLKKTEIRLEQNRAQLIDLIVKGLRIIKGERFEKMDVLPGPPHEVLETYKNEPVTVAMLEDLIADVKLHIDVDTTVVDADFQDFWKSLLVLAREALERAKKRKDVLDQLARNSSPQMAAEAAAQLADTVCPQIRDADTGIVLSVAHEIEGLLGGKSAAELDELEAQIRSKFEEEDIDVAYWEGILNKIPSFRARAVCLQTWHMMTQSAADAEREMAREKALKEEEEAKAARAKGEELEGLLLEEADARKLARAQQIKQDAIKVARSVEKDVNPNADGSFSPELEPYDEGEVPPPVRGPYSPQLWPFDEFRHAEILAPDDDEDRRAILKKTLIQKERLKRAGLEEDPEPTPEAAENDASLDVLDPAAKVTTYEEFVKKEKKNLEADEEVMASSSEHKLTMHYTWEEKYRPRKPRFFNRVKTGYSWNKYNTTHYDHDNPPPKVVQGYKFNIFYPDLIDKTKAPTWFLEPSDTPDTVIIRFHAGPPYEDIAFKILNQEWQLERFRGFRNVFDRGIMQLYFSFKRYIYRR