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bur6

Gene
bur6
Protein
Transcription regulator complex subunit bur6
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Length
199 amino acids
Function
Transcription regulator complex subunit that is essential for cell cycle progression.
Similarity
Belongs to the NC2 alpha/DRAP1 family.
Mass
22.236 kDa
Sequence
MGDPTNNNDSETKPNPATYWKSRFPVARIKKIMQADQDVGKVAQVTPVIMSKALELFMQSIIQESCKQTRLHQAKRVTVSHLKHAVQSVEQFDFLQDIVEKVPDAPPIKAERKTKRPRARRAANEGEHNESVPAKKVKKNTVKEEEIEKDDESATTETPVKEEPTGEETEADHEEKASVDHGNFSDKTTSEASSASGDE

Gene
BUR6
Protein
Negative cofactor 2 complex subunit alpha
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
142 amino acids
Function
Component of the NC2 complex which represses RNA polymerase II transcription through binding to SPT15/TBP and thereby inhibiting the assembly of the preinitiation complex. The NC2 complex may also mediate transcriptional activation from TATA-driven promoters through association with SPT15/TBP.
Similarity
Belongs to the NC2 alpha/DRAP1 family.
Mass
15.517 kDa
Sequence
MADQVPVTTQLPPIKPEHEVPLDAGGSPVGNMGTNSNNNNELGDVFDRIKTHFPPAKVKKIMQTDEDIGKVSQATPVIAGRSLEFFIALLVKKSGEMARGQGTKRITAEILKKTILNDEKFDFLREGLCVEEGQTQPEEESA