Protein
Putative anti-sigma factor antagonist BtrV
Organism
Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50)
Function
Possible positive regulator of sigma-B activity (By similarity). Non-phosphorylated BtrV binds to BtrW, preventing its association with an unknown partner(s) that might be sigma-B. When phosphorylated, releases BtrW, which is then free to complex with and inactivate its partner. Involved in type III secretion system (TTSS).
Similarity
Belongs to the anti-sigma-factor antagonist family.
Sequence
MKLTMDKIDGMLIACLQGVVNSANAEQLEAELAAQVDKGERRVVLDLGRLDYISSAGLRVVLLVAKQLRQVQGELVLCELKPHVREVFEISGFLSIFPVANSREAAAAAFKTALPR