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bshB2

Gene
bshB2
Protein
Probable N-acetyl-alpha-D-glucosaminyl L-malate deacetylase 2
Organism
Bacillus anthracis
Length
226 amino acids
Function
Involved in bacillithiol (BSH) biosynthesis. Catalyzes the second step of the pathway, the deacetylation of N-acetylglucosaminylmalate (GlcNAc-Mal) to glucosamine malate (GlcN-Mal). Could also be involved in bacillithiol-detoxifying pathways through formation of S-mercapturic adducts.
Similarity
Belongs to the PIGL family.
Mass
25.857 kDa
Sequence
MKNERHVLIVFPHPDDESYCVAGTILAYTQRNVPLTYVCLTLGEMGRAMGNPPFATRESLYAIREKELKRATNILGIKDLRMMGYRDKTLEFETPGELRRVIQKCVEELNPSLVISFYPGYAVHPDHDATGEAVAEALATIPENKRPTFYAVAFANNHEAEIGPPHVKNEVKEYVPKKLEALQAHASQFATKVTELKREYEDGVTETVEWLEREPFWIYPFKDKNK

Gene
bshB2
Protein
Probable N-acetyl-alpha-D-glucosaminyl L-malate deacetylase 2
Organism
Bacillus subtilis (strain 168)
Length
221 amino acids
Function
Involved in bacillithiol (BSH) biosynthesis. Catalyzes the second step of the pathway, the deacetylation of N-acetylglucosaminylmalate (GlcNAc-Mal) to glucosamine malate (GlcN-Mal).
Similarity
Belongs to the PIGL family.
Mass
25.577 kDa
Sequence
MKEHVLVILPHPDDESYGVAGLIALNRKKDIPVTYACATLGEMGRNMGDPFFANRETLPLLRKQELINACKEMDINDLRMLGLRDKTLEFEDDEYLADIMEEIIDDVKPSLIVTFYPGHGVHPDHDACGEAVIRALYRKKKEDRPRTICMAITRNREEVLGEADVVLDIKEVADIKMNALRAHRTQTEGMLRELEEKLKNNEPVMATWFEEEIYWTYQWND

Gene
bshB2
Protein
Probable N-acetyl-alpha-D-glucosaminyl L-malate deacetylase 2
Organism
Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NRRL B-3711)
Length
220 amino acids
Function
Involved in bacillithiol (BSH) biosynthesis. Catalyzes the second step of the pathway, the deacetylation of N-acetylglucosaminylmalate (GlcNAc-Mal) to glucosamine malate (GlcN-Mal). Has weak activity compared with bshB1.
Similarity
Belongs to the PIGL family.
Mass
24.92 kDa
Sequence
MERHVLVVFPHPDDEAYAAGGTIRLLTDQGVPVTYACGTLGQMGRNMGKNVFANRETIPHIRKKELKDACEAMGIKDLRMLGFHDKTLEFEDVDFVADKIEAIIQEVNPSRIITFYPEHGVHPDHNAFGRAVVRAVSRMPKEERPVIHAVAITKNREAVLGEPDVVNNISEVFDHKLTALGAHRSQTEAMLEDTHAKIKNKDAATLKWLQLEQFWTYKWE