Protein
Aspartate/glutamate leucyltransferase
Organism
Novosphingobium aromaticivorans (strain ATCC 700278 / DSM 12444 / CIP 105152 / NBRC 16084 / F199)
Function
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
Similarity
Belongs to the R-transferase family. Bpt subfamily.
Sequence
MTAPVRFPRFFVTSPAPCPYLPGRSERKVFTELKGANADELNDALGRIGFRRSQTVAYRPSCIDCQACVSVRVVTGEFRPSSTQKRIHKRNRDLEVSICKAWSTPEQFELLQRYLAVRHPGGGMAAMDEMDFADMVEHTPVKSYVIEYREPTVDGSQGRLVGACLTDEQGDGLSMIYSFYDPQHETRSGLGTFIILDHIQRAARAGLPYVYLGYWVEGSERMQYKVRFRPMEKLGRDGWERFEPAEQASAIERAVTARKCEPASLVEGSLKDGVHGAQERYAHI