Function
Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of chromosome segregation and cytokinesis (PubMed:12707312, PubMed:10209096, PubMed:10983970). The CPC complex has essential functions at the centromere in ensuring correct chromosome condensation, alignment and segregation (PubMed:12707312, PubMed:10983970). In the complex, required to direct the Aurora B/air-2 kinase to chromosomes (PubMed:12707312, PubMed:10983970). Also functions in spindle midzone formation and in the formation of polar bodies during oogenesis (PubMed:10209096, PubMed:10983970). Required for the localization of the kinetochore component hcp-1 to chromosomes (PubMed:10983970). Involved in the positive regulation of transcription (PubMed:12682297). Involved in the transcriptional regulation of collagen genes (PubMed:17116281).