Protein
Translocator protein BipD
Organism
Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 / E264)
Function
Required for invasion of epithelial cells, as well as for survival within host cells, escape from endocytic vesicles and subsequent actin-tail formation. Probably regulates the secretion of effectors BipB and BipC and their final integration into the target cell membrane (By similarity).
Similarity
Belongs to the invasin protein D family.
Sequence
MNVQVDMGRALAARDWRAVAALAVAMPAHAGAGTITDDDLRAAGVDRRVPEQKLGATIDEFASVRLPEQIDGEFVEGRRANLAVFDDARVAVRSHALAQRNLLERWETEHLGGTLDAAGSGGGIQPDPILQQLVDVIAQGKSDVDAYATIVEGLTKYFQSVADVMSKLQDYISAKDDKNMKIDGGKIKALIQQVIDNLPKMQLPKGADIARWRKELGDAVSISDSGVVTINPDKLIKMRDSLPPDGTVWDTARYQAWNTAFSGQKDNIQNDVQTLVEKYSHQNSNFDNLVKVLSGAISTLTDTAKSYLQI