bioF1

Gene

bioF1

Protein

8-amino-7-oxononanoate synthase 1

Organism

Polaromonas sp. (strain JS666 / ATCC BAA-500)

Length

405 amino acids

Function

Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.

Similarity

Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.

Mass

42.929 kDa

Sequence

MAINTPLTNSWLDEFPARIAELDRAHLRRRRRVVVPEDGAHLQVDGQRMLAFCSNDYLGLAGHPALVQAACDGARAFGVGAAASPLVSGHSAANEALEAALARFVGQPRALYFYAGYATNIGIVPALVGKGDAIFSDALNHACLIDGARLSSAQIHRYPHADLAALEQELISSPARRKLIISDAVFSMDGDVADVPALLALCERHDALLLLDDAHGFGVLGPQGRGCLAHFGLSGENASPRVLYMATLGKAAGVAGAFVAGSEALVEWLLQKTRSYIFATAAPALLATALQTSLQLIEQDEWRREHLQRLIARLRSGLAQGLQGSSWRLGESPTAIQPVVIGPNDAALAVMEGLRTRGLWVPAIRPPTVAEGTARLRIALSAAHTEADIDRLVQALTELAKPGSL

Protein

8-amino-7-oxononanoate synthase 1: bioF1

Gene

bioF1

Protein

8-amino-7-oxononanoate synthase 1

Organism

Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)

Length

386 amino acids

Function

Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.

Similarity

Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.

Mass

40.028 kDa

Sequence

MKAATQARIDDSPLAWLDAVQRQRHEAGLRRCLRPRPAVATELDLASNDYLGLSRHPAVIDGGVQALRIWGAGATGSRLVTGDTKLHQQFEAELAEFVGAAAGLLFSSGYTANLGAVVGLSGPGSLLVSDARSHASLVDACRLSRARVVVTPHRDVDAVDAALRSRDEQRAVVVTDSVFSADGSLAPVRELLEVCRRHGALLLVDEAHGLGVRGGGRGLLYELGLAGAPDVVMTTTLSKALGSQGGVVLGPTPVRAHLIDAARPFIFDTGLAPAAVGAARAALRVLQAEPWRPQAVLNHAGELARMCGVAAVPDSAMVSVILGEPESAVAAAAACLDAGVKVGCFRPPTVPAGTSRLRLTARASLNAGELELARRVLTDVLAVARR

Protein

8-amino-7-oxononanoate synthase 1: bioF1

Gene

bioF1

Protein

8-amino-7-oxononanoate synthase 1

Organism

Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

Length

386 amino acids

Function

Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide (By similarity). Can also use pimeloyl-CoA instead of pimeloyl-ACP as substrate. To a lesser extent, can also utilize D-alanine instead of L-alanine as substrate.

Similarity

Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.

Mass

40.028 kDa

Sequence

Protein

8-amino-7-oxononanoate synthase 1: bioF1