Protein
ATP-dependent dethiobiotin synthetase BioD
Organism
Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)
Function
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring.
Similarity
Belongs to the dethiobiotin synthetase family.
Sequence
MSVLVITGTGTEVGKTVTTAAVAAVAVAAGRSVAVLKPAQTGVRPDERGDADEVARLAGAVTTLELARYPEPLAPATAARRAGLPPVGPHEVAEAAAKLAVEHDLVLVEGAGGLLVRFDDADGTLADAARLLDAPVLVVASAGLGTLNTTELTARELRRREIGFAGVVIGSWPESPDLASRCNLADLPAVAGAGLLGAIPAGAGAHSPVGFRAGAPGWLAPRLGGTWDADTFASAFVP