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axeA1

Gene
axeA1
Protein
Acetylxylan esterase
Organism
Prevotella ruminicola (strain ATCC 19189 / JCM 8958 / 23)
Length
480 amino acids
Function
Involved in degradation of plant cell wall polysaccharides. Is an acetyl esterase with broad substrate specificity, releasing acetic acid from acetylated xylo-oligosaccharides and acetylated xylan as well as xylose-tetraacetate, 4-O-methylumbelliferyl acetate, glucose-pentaacetate, and cephalosporin C. Appears to have greater activity on oligosaccharides than on polymeric substrates. Is also able to release acetic acid from xylo-oligosaccharides with 4-O-methylglucuronic acid side groups proximally located to O-acetyl esters. Preferentially targets xylo-oligosaccharides possessing three or more O-acetyl groups, but following their depletion it is active on the less acetylated portion of the substrate.
Similarity
Belongs to the AB hydrolase superfamily.
Mass
53.109 kDa
Sequence
MNRKLFMTGLLMLAMTMQAQTAKKFTLNLSDDGKAQMVCFLPENPSGRAIVGVPGGGYSMLSNTHEGYQASDWLNKQGIAYFVVNYRLPHGDRTIPVGDVEQGFRIVRDSAKVWNINPNDVGIMGFSAGGHLSSVISTMSPYEVRPNFSILFYPVISMDERVSHKWSCINFLGKEGYKDPKLIGQYSTQNAVRSHLTPPACIISANDDRLVPVVTNGIQYYSAMRNAGNECSLFIYPSGDHGFGFGTWFKYHDQLLQDLGNWLKSIPAPKEDAIRVACIGNSITDGFGIDMRAKYGYPAQLQGILGDGYWVKNFGVSARTMLNKGDFPYMNEMAWKDALAFKPDVVVIKLGTNDSKPENWQYGSEFRQDLEQMIKALRPDLAQPAKKGKKKAKAAAQPAGPKILLCTPIPAFKPSWNINDKVITDEIIPIQQEVAKQYGLQIIDLHALMLNDGDKVVDDGIHPNEKGAKKMAEIIAAAIK