aspS2

Aspartate--tRNA(Asp/Asn) ligase 2

591 amino acids

Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).

Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.

67.123 kDa

MSDFITIKKRTHYCGQLDSSDSGKEVILMGWVHRRRDHGGVIFVDFRDREGLVQIVFNPEYSPVAHQEAHKIRSEYVLAVRGAVRNRPEGMVNPDMKTGAIEVMVEELEILNESQTPPFSLESESDISENIRLKYRYLDLRRPQIQRNIMLRNRVAAETRQFFQSNGFIEIETPFLTKSTPEGARDYLVPSRINKGTFYALPQSPQIFKQLLMVSGFDRYFQIVKCFRDEDLRADRQPEFTQIDVEMSFITEDDIIEIMEGLMTHLFSRCLNRTFSTPFPRLSYAEAIGRYGKDNPDIRFGLELRDLTDILADSGLTVFREAAAGGGMIKAIRIPEGKRLSRKDLDDLQNFVSIYGARGLAWARVLADGWTSPIFKFLTADEVRQINGRMEAVEGDVLVFVADTPTVVNDSLGNLRIHLAKKLNLIDPEQFAFVWITEFPLMEFSDTEKRYVSTHHPFTSPVPDDVKYLPGEPGKVRARAYDLVLNGSEVGGGSIRIHRKEIQSLIFEALGLENEEVRSKFGFLLDALEFGTPPHGGIAFGLDRLVMMMTGAESIRDVIAFPKTQKATCLMTDAPSRVSIEQLMELSLKIV

aspS2

Aspartate--tRNA ligase 2

589 amino acids

Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).

Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.

66.967 kDa

MKRSMYAGAVRSEHIGQELTLKGWVARRRDLGGLIFIDLRDREGIVQLVINPKTASNTVVKSAESLRSEYVIEVTGMIVERDQANDNLPTGCVEMQVTQLTILNASQTPPFEIKDKIEANDDTRLRYRYLDLRRPEMLKNFKLRAKVTHVIRNYLDDLDFIDVETPMLAKSTPEGARDYLVPSRMSRGHFYALPQSPQITKQLLMNAGFDRYYQIVKCFRDEDLRGDRQPEFTQVDLETSFLSEQEIQEITERLIACVMKEVKGIELQLPLPQISYDTAMNNYGSDKPDTRFEMTLQDLTDLVKNIDFKVFSQAPAVKAIVAKNAANSYSRKAIDKLTDIVKPFGAKGLAWVKYNDGKIGGPIAKFLTTIEDELIERLQLEANDLVFFVADDLEIANGSLGALRNHLAKELNLIDHSKFNFLWVVDWPMFEWSEEENRYTSAHHPFTLPQEDTVAELEGDLSKVRAVAYDIVLNGYELGGGSLRINQRETQERMFKALGFTKESAQKQFGFLLEAMDYGFPPHGGLALGLDRFVMLLAGKENIREVIAFPKNNKASDPMTQAPSLVSDKQLDELYLQVNKNAVKNNEQE

aspS2

Aspartate--tRNA ligase, cytoplasmic 2

569 amino acids

Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.

67.218 kDa

MSEENNHKEKSKNEIKKEKKKIEKEKKITELKSKKKINEKNNTINYDDDDDNDDDNFKNKKWGEINNENYKEIIKNRFVKEWSNISDLNESCVGKYVLIRARVSNIRSFGNSLCFLQLRDGLSSIQAVISKNDENNSKSMIHFINSTITKESIIDIEAILTNSSTPIESCIIKNLELKIYSLFLQSKSNSSLPLQFDDLSKPTTYQNYDDNGYTYVIPLNSRLNNRCLDLRTFYNLSIFKIQSAISNLFRDQLLINDFIEIHSPKIIKQSINENSFKLNYFNEIAYLSESTQFYRQLAIVSDFKRVFEIGPVYRTDLGHTHRHLNEFTSLDFEMTFKDHYHEVLDFLDNLMISIFKILETNYENELKIINNYQLQFEKFKFSTKTPRFTFSEVKLMLIEFSENENNKFCMELFDYLNVQEERIFGKIVKEKFNVDYYIIEKPSSEYQPFYIMPDSNNEKLLNSFHIYINGEKIGSGSQRIHDWKLLEKRYKNYYINHNNNNNNNNNNNNNNNNNNNNNNIENYINIFKFGCSQHAGCSIGLERLVMAYLGLENIRKASFCPRDPTRLTP

aspS2

Aspartate--tRNA(Asp/Asn) ligase

435 amino acids

Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn). Is slightly more efficient at aminoacylating tRNA(Asn) over tRNA(Asp).

Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.

48.231 kDa

MTSPLKRTLTRELPQHEGQTVKLQGFVHARRDLGGVQFLVLRDVTGVTQCVGSGLTLPLAESSVEVVGKVKAHPKAPGGFEVQVEDFRVISAATEATPVEIPKMEWNVNPETMLDYRVVTVRGLKERAALKVQAELVDAFRAHLRGEGFTEISTPKIVSAGAEGGANLFPIDYFGHPAYLAQSPQLYKQIMVGVFERVFEVAAVYRAEEHATSRHLNEYLSLDVEMGFIEDEEDVMGLENRLLASIMERLRATSQAEFELLGATIPDVPAHIPRITLMDARQLVTEKYGHPVGGKDLDPEAERLLSQHFAETEGSDFVFVTKYPRAARPFYAHPELNEDGSVNGEVTRGFDLLFRGIEITSGGQRIHDYGMLMDSIAAYKLKPESLEGYTEVFKYGMPPHGGFAIGAERLTAKLLGIANVRYARAFPRDRHRLTP

aspS2

Aspartate--tRNA(Asp/Asn) ligase

422 amino acids

Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn) with similar efficiencies. Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).

Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.

48.329 kDa

MRVLVRDLKAHVGQEVELLGFLHWRRDLGRIQFLLLRDRSGVVQVVTGGLKLPLPESALRVRGLVVENAKAPGGLEVQAKEVEVLSPALEPTPVEIPKEEWRANPDTLLEYRYVTLRGEKARAPLKVQAALVRGFRRYLDRQDFTEIFTPKVVRAGAEGGSGLFGVDYFEKRAYLAQSPQLYKQIMVGVFERVYEVAPVWRMEEHHTSRHLNEYLSLDVEMGFIADEEDLMRLEEALLAEMLEEALNTAGDEIRLLGATWPSFPQDIPRLTHAEAKRILKEELGYPVGQDLSEEAERLLGEYAKERWGSDWLFVTRYPRSVRPFYTYPEEDGTTRSFDLLFRGLEITSGGQRIHRYEELLESLKAKGMDPEAFHGYLEVFKYGMPPHGGFAIGAERLTQKLLGLPNVRYARAFPRDRHRLTP