About Products Protein Database Contact

arpC

Gene
arpC
Protein
Antibiotic efflux pump outer membrane protein ArpC
Organism
Pseudomonas putida
Length
484 amino acids
Function
The outer membrane component of an antibiotic efflux pump. Confers resistance to numerous structurally unrelated antibiotics such as carbenicillin, chloramphenicol, erythromycin, novobiocin, streptomycin and tetracycline. Is not involved in organic solvent efflux.
Similarity
Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
Mass
52.834 kDa
Sequence
MTKSLLSLAVTAFILGGCSLIPDYQAPEAPVAAQWPQGPAYSPTQSADVAAAEQGWRQFFHDPALQQLIQTSLVNNRDLRVAALNLDAYRAQYRIQRADLFPAVSATGSGSRQRVPANMSQTGESGITSQYSATLGVSAYELDLFGRVRSLTEQALETYLSSEQARRSTQIALVASVANAYYTWQADQALFKLTEETLKTYEESYNLTRRSNEVGVASALDVSQARTAVEGARVKYSQYQRLVAQDVNSLTVLLGTGIPADLAKPLELDADQLAEVPAGLPSDILQRRPDIQEAEHLLKAANANIGAARAAFFPSISLTANAGSLSPDMGHLFSGGQGTWLFQPQINLPIFNAGSLKASLDYSKIQKDINVAKYEKTIQTAFQEVSDGLAARKTFEEQLQAQRDLVQANQDYYRLAERRYRIGIDSNLTFLDAQRNLFSAQQALIGDRLSQLTSEVNLYKALGGGWYEQTGQANQQASVETPKG

Gene
arpC
Protein
Actin-related protein 3
Organism
Dictyostelium discoideum
Length
418 amino acids
Function
Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament. The Arp2/3 complex is involved in organizing the actin system in cell motility and chemotaxis, in phagocytosis and macropinocytosis, at late steps of endosome processing, and in mitosis. In concert with a group of other proteins, the Arp2/3 complex plays a general role in the rapid activation and adaptation of the actin system to its multiple functions.
Similarity
Belongs to the actin family. ARP3 subfamily.
Mass
46.698 kDa
Sequence
MNPASGLPAVVIDNGTGYTKMGYAGNNDPSFIIPTTIATQSSKGKQTAASQKKGVEDLDFFIGDEAIANSKTYDMTNPVKHGQIENWTHMEQYWEHCVFKYLRCEPEDHYFLLTEPPLNAPENREFTAEIMFETFNVPGLYIAVQAVLALAASWTSKNAEKTLTGTVIDSGDGVTHVIPISEGYVIGSSIKHIPIAGRDISSYVQQIMREREPNIPPAESLEIAKRVKEQYSYVCPDIVKEFGKYDSEPDKWIKTINAQDSVTKKPFSYDVGYERFLGPELFFNPEIASSDYLTPLPKVVDDTIQSCPIDCRRGLYKNIVLSGGSTMFKDFGKRLQRDVKRSVDYRIKRSEELSGGKIKAVPLAVNVISHNMQRYAVWFGGSMLASTPEFYNVCHTKAQYDEIGPSICRFNTVIGGIN