Protein
Aminoglycoside 3'-phosphotransferase
Organism
Streptomyces fradiae
Function
Resistance to kanamycin and structurally-related aminoglycosides, including amikacin.
Similarity
Belongs to the aminoglycoside phosphotransferase family.
Sequence
MDDSTLRRKYPHHEWHAVNEGDSGAFVYQLTGGPEPQPELYAKIAPRAPENSAFDLSGEADRLEWLHRHGIPVPRVVERGADDTAAWLVTEAVPGVAAAEEWPEHQRFAVVEAMAELARALHELPVEDCPSDRRLDAAVAEARRNVAEGLVDLDDLQEERAGWTGDQLLAELDRTRPEKEDLVVCHGDLCPNNVLLDPGTCRVTGVIDVGRLGVADRHADIALAARELEIDEDPWFGPAYAERFLERYGAHRVDKEKLAFYQLLDEFF