Protein
Alpha-delta-bungarotoxin-2
Organism
Bungarus candidus
Function
Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission.
Similarity
Belongs to the snake three-finger toxin family. Long-chain subfamily. Type II alpha-neurotoxin sub-subfamily.
Sequence
YTLLCYKTPIPINAETCPPGENLCYTKMWCDIWCSSRGKVVELGCAATCPSKKPYEEVTCCSTDKCNPHPKQRPD