aftB

Terminal beta-(1->2)-arabinofuranosyltransferase

686 amino acids

Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component of the cell wall. Catalyzes the transfer of arabinofuranosyl (Araf) residues from the sugar donor decaprenyl-phospho-arabinose (DPA) to the arabinan domain to form terminal beta-(1->2)-linked Araf residues, which marks the end point for AG arabinan biosynthesis before decoration with mycolic acids.

Belongs to the AftB family.

75.84 kDa

MTFSPQRPEFETGKQPDPETEHAGDFFEETSSSAPRAASNGSSGPNYTLITTFLAALTAGIFAFWAGWTRKWISDDGLIVLRTVRNLLAGNGPVFNAGERVEANTSTLWQYCIYLVALVTDYRLEDIALWLALLFTTAASIIGVLGTAHLHRKRIAVLLPAGVIGYFSLSPARDFATSGLEWGLSLMWISIQWLLLVLWATSGKTSGKKASGAKTSNPIVNAGAITYALAFWSGLSWLVRPELAMYGGLTGVLLLLTAPRWRVVLGILVAALPLPAAYQIFRMGYYGLMVPHTAVAKSASDAVWGTGWEYVEDFTGPYNLWLGLALLLAAGALTVWKTDKHLAIPKGRLGLRTPGMAIALLVICALVHFLYVIRVGGDFMHGRMLLLPLFAILLPVSVIPVNVVDRGWQDLVALVLVFSTWVWSTVVFVQGHQWENTGQHVVDERDFWIDFTNRDEDHPPLYAEDFLTVDSMNDYAEVMRDQTLVNPTGQQLNILASSDPTTYSWITTPRVEGVEAGDLANLSPTVFHVNLGMTSMNAPLNVRVTDLIGLATPLAARQPRIEGGRIGHDKLMDLEWQVAESATPLAYTPGWLDTQKTYEARQALRHPELVHLFQTYREPMSYHRFVDNIKYALTTGRTLEISDNPEDLLKEFNPTPAEIQDGLETIAWPGEIKLDEPRGEPLYSSQ

aftB

Terminal beta-(1->2)-arabinofuranosyltransferase

627 amino acids

Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component of the mycobacterial cell wall. Catalyzes the transfer of arabinofuranosyl (Araf) residues from the sugar donor decaprenyl-phospho-arabinose (DPA) to the arabinan domain to form terminal beta-(1->2)-linked Araf residues, which marks the end point for AG arabinan biosynthesis before decoration with mycolic acids.

Belongs to the AftB family.

68.71 kDa

MVRVSLWLSVTAVAVLFGWGSWQRRWIADDGLIVLRTVRNLLAGNGPVFNQGERVEANTSTAWTYLLYVGGWVGGPMRLEYVALALAMVLSLLGMVLLMLGTGRLYAPSLRGRRAIMLPAGALVYIAVPPARDFATSGLESGLVLAYLGLLWWMMVCWSQPLRARPDSQMFLGALAFVAGCSVLVRPEFALIGGLALIMMLIAARTWRRRVLIVLAGGFLPVAYQIFRMGYYGLLVPSTALAKDAAGDKWSQGMIYVSNFNRPYALWVPLVLSVPLGLLLMTARRRPSFLRPVLAPDYGRVARAVQSPPAVVAFIVGSGVLQALYWIRQGGDFMHGRVLLAPLFCLLAPVGVIPILLPDGKDFSRETGRWLVGALSGLWLGIAGWSLWAANSPGMGDDATRVTYSGIVDERRFYAQATGHAHPLTAADYLDYPRMAAVLTALNNTPEGALLLPSGNYNQWDLVPMIRPSSGTAPGGKPAPKPQHAVFFTNMGMLGMNVGLDVRVIDQIGLVNPLAAHTERLKHARIGHDKNLFPDWVIADGPWVKWYPGIPGYIDQQWVTQAEAALQCPATRAVLNSVRAPITLHRFLSNVLHSYEFTRYRIDRVPRYELVRCGLDVPDGPGPPPRE