adrC

ABC-type transporter adrC

1452 amino acids

ABC-type transporter; part of the gene cluster that mediates the biosynthesis of the meroterpenoid compound andrastin A, a promising antitumoral compound (PubMed:28529508). Is required for the production of andrastin A but does not have a significant role in its secretion (PubMed:28529508).

Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.

162.812 kDa

MAPEEGDQAMSHEDKAACSSLNTTSSTELFDGAPSSENERLRIRQAAVDAMHHGSPKIDPQIWTDVTSHLSGSTTIDARQRDIFFENLTVHGKGSSLQIQKTVLSALLYPIAYPVKRLMSIVGNKKPHNDRRTILHGFNGILNSGELLLVLGRPGSGCSTFLKSLCGYLEGLDLDPVSEIQYRGVPFRVMIEKYRGDLVYNQEADHHFPNLTVGQTLEFAAHARAPHNQVGNSSRDQYVKSVVKVVMDTFGLSHTYDTNVGNDFVPGVSGGERKRVRTDTIVGMNSIAETVLSRTSIAAWDNSTRGLDAATAVDFVRSLRTSAKLAGSCHAVAVYQASEGLYNTFDKVILLYEGREIYFGPRQGAVAYFETMGWKRPPQQVSADFLTAITNPGERQPQVGMENAVPRTPVEFESYWKNSPEHAELETSMRQYKMKTPLDSSEEIKLDEIKRLEQSNHARISSPYLLSVPMQIRLCIVRAWQRTRNDIPALIATAVAQTVVSLIIGSLFYNIPENTAGLGQRASVLFLAVLTNALISLLEITTLYSQRLIVEKQAAYAFVHPFTEAIAEVIVDFPIKLFRCLLSAIIVYFLANLRREASHFFIYIMFQLTAVMTMATIFRTLATVTRTIGQAMALAGVVIICIAVYTGFTVPQFDMPPWFGWIRWLNPIFYTFEGIVSNEFHGRHFECVEYIPSLSFEQGLSFTCSYVGSIAGERYVSGDAYIAGSYDYSYDHVWRNYGILVAFLVFFYVLYFWLTELIPGTTPAHEVLIFRHGGVLQRLVRGDLERGESIRLQEVKSLASEVHSSKAEQKNTFSWKGLSYDIPVKGGEKRLLDDVSGWVKPGSLTALMGVSGAGKTTLMNVLARRMTIGVVTGDMFVNGRELDASFARNIGYVQQQDLHVETCTIREALRFSAALRQPQSVSMEEKYNFVEEVIQLLGMQNFAEAVIGSPGDGLNMEQRKLLSIGVELAAKPQLLIFLDEPTSGLDSRSSWAICAFMRKLADHGQPVLATIHQPSAVLFEQFDRLLFLAKGGRTVYFGDIGKQARTVLEYLEDKGARHCGPTENPAEYMLEVIGGGTQGQSTSIDWVQAWKRSTEYNKLLGELDILASSPSNGVSADPYMVGEFAMPLLVQFYHVMKRDLQQYYRQPEYILAKFGAGVFCGVFIGFSFWKSDNSSQGFQNVLFSLFLLCTIFSTLVNQIMPKFLSRRTLYELRERPARTYSWKVFILCQILVELPWQTLLGICTWASFYFSVYGSGQSSQRQGLVLLFTVQFFIFASTFAQLVVAAVPSVVLGSMLATFTFLLCLLFNGTMQPPSALPRFWIFMNRVSPLTYYVGGISATALHGRPIHCSNRELRVFDPPQGQNCGQYLAEYLKTAQGTLSNPLSTDQCQYCPLRVADQYLAARDISWDDRWRNFGIFWVYIIFNVIGAVLLYYLFRVLPYIRRNRTQKSRN

adrC

ABC-type transporter adrC

1442 amino acids

ABC-type transporter; part of the gene cluster that mediates the biosynthesis of the meroterpenoid compound andrastin A, a promising antitumoral compound (Ref.2). Is required for the production of andrastin A but does not have a significant role in its secretion (By similarity).

Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.

161.327 kDa

MAPDEGDQAMSLQEEKPAYPSLSTTSSAELLHGAPLNDNERLDILQTAEHAMHRGSPKVDPHIWTNVTSHFSDSSTIDGRQRDILFERLTVRGKGSPFQIQQTILSALLYPLAYPIKRLVKLVGKKESHDGPGTILRGLNGIVCSGELLLVLGRPGSGCSTFLKSLCGYLEGLDVDTASEIQYKGVPFTTMMEKYRGDVVYNQEANHHFPNLTVGQTLEFAAHARAPHNRAGNQRGDQCQWRGKKESQVSLALFSLGGERTEGKAMRTDTVGMNSIAETVLSRASIVAWDNSTRGLDAATAVDFVRALRTSAKLSGSCHALAVYQASETLYNTFDQLILLYEGREIYFGSRERAVPYFESMGWKRPPQQVSADFLTAITNPGERQPQVGMEHAVPRTSLEFEAYWKSSPEHAELQRSMQQYKQKTPLDISEEIKLDEVKRLEQSTHARPSSPYLLSVPMQIRLCIVRAWQRTRNDIPGLVSSAVAQIVVSLIIGSLFYNIPQTTAGLGQRGSVLFLAVLTNALISLLEINTLYSQRLIVEKQAAYAFVRPFTEAIAGVIVDFPVKLFRCALSAIIIYFLANLRREASHFFIYILFQLTAVMTMATMFRTLATVTRTIGQAMSLAGVIIICVAVYTGFTVPQFDMPPWFAWIRWVNPIFYAFEAIVANEFHGRHFECVEYIPSLSFQEGLSFTCSYVGSVPGERYVSGDAYIAGSYDYSYDHVWRNYGILVAFLVFFYVLYFWLTELIPGTTPTHEVLIFRRGDAHPKLSRSDLESGEQPRPLQELKSLAPPAHPSMAEQKDTLSWNGVCYDIPVKGGEKRLLDDVSGWVKPGSLTALMGVSGAGKTTLMNVLARRMTIGVVTGDMLVNGHEPDASFSRKTGYVQQQDLHVETCTIREALRFSAALRQPQSVSTEEKYKFVEEVIQLLGMEDFAEAVIGNPGDGLNTEQRKLLSIGVELAANPQLLIFLDEPTSGLDSRSSWAICKFMRKLADNGQPVLATIHQPSAVLFEQFDRLLFLAKGGKTVYFGDVGHQARTVLEYLEKNGARQCGPTENPAEYMLEVIGGGTQGQSTPIDWVHAWKNSSENTQVLEELDSLVSSPSNAIPADPCKLSEFAMPLAVQFHHVMKRDLQQYYRQPEYILAKFGAGIFCGLFIGFSFWSSDNSSQGFQNVLFSLFLLCTIFSTLVNQIMPKFLSRRALYELRERPAKTYSWTVFILCQILVELPWQTLLGICTWASFYFSVYGDDQSPQRQVLILLFTVQFFLFASTFAQFVIAAVPNLVLGSMMATFTFLLCLLFNGIMQPPSALPRFWIFMNRVSPLTYYVGGISATALHGRPIHCSNRELRVFDPPQGQTCGQYLAEYLKTAQGTLHNPLSSDRCQYCPLRVADQYLAARDISWHDRWRNFGVFSVYIIFNIIGAIGLYYLVRVLPYAMKNRTQKSPT