Organism
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)
Function
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.
Similarity
Belongs to the adenylate kinase family. AK2 subfamily.
Sequence
MAPITEEVVHGLKDMIEKLENRVQELEGRLGGESKPKSIAEQMRIVLMGPPGAGKGTQAPRLKEKYCVCHLATGDMLRSQVAKKTELGKEAKKIMDQGGLVSDEIMVNMIKNELDTNTECKNGFILDGFPRTVAQAERLDDMLEARKQKLQHAIELQIDDALLVARITGRLVHPASGRSYHKIFNPPKNDMKDDVTGEPLIQRSDDNAETLKKRLSTYHAQTAPVVEYYKKTGIWRGIDASQEPGQVWKSLLGVFQK