Protein
ABC multidrug transporter B
Organism
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)
Function
Pleiotropic ABC efflux transporter that may be involved in A.fumigatus adaptation to azoles such as vorizonazole.
Similarity
Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
Sequence
MTGSSPPLSCQQVDNTLHIPALSCRGGFDFSLLFEELILGILPLGIVLIIAPFRLYHLFWRQAKVVASWLLWAKITAWLALGIVQLVLAVYWARPAATRTQASIAANAIITVGFFILCLLSCAEHLRSTTPSFLLNIYLLFTLLFDIAKTRTLWLRSSGQTDETIAILTSVTVGIKFLLLILEAVEKRHILRKGQSGYPPEATAGIFNRSFFLWLNPLFRSGFSKILDVEDLFDLDKHLSSRRLYSTLETLWDKVPKKNPNTLLFISLKAFKWPLLSAVPPRACLAALNFCQPLLLHRSLAFATEPVNNHTNSIGYGLIGAYILVYIGMGVTMGQYQHMTYRTITMVRGGVVSMIYNKASRLGIKDADPAASLTLMSADIERIVQGWQTIHDIWGNAAEIALAIYLLERELGVACVVPVGVALVALIGCLITLSFVVARQAVWLEAIERRISSTASMLSSMKGIKMLGLKSAIMKSLHGLRLEELEISKKFRRLLVWNMALGWTTRIFAPIFALGAFYGIMHSRGKDSAFDMSTAYTSLSLFALLADPLLSLVMALMTFVGSIGSFSRIQEFLEKDDHVDCRLKPLHASYESFEPKAMVLVDDSDATETASDRSIHRGKSVYHDALTVKNATFAWNVEKEPVLKGLTISIARGSFTMIVGPSGCGKSTLLKAILGEVPCVNGEIRLSSDSIAFCDQIPWHMNATIRESIVAMSSFDKEWYASVVHACGLVQDFEQLPRGDETVIGSKGIALSGGQSQRIALARAVYARKDIVILDDAFSGLDAATEDYVFHSLVGIHGLLRKINSTIIVASSSAKRLPYADQIVVLDKMGYASEQGSLKALNAAGGYVSSFGLGSPEWKSEIDKPSVTDLAQPKILRPNRTEAIKEDPRRQSGDLSIYLYYIRSIGWLPTRLVLTDMTGIWVKWWAISNEEDPNGRTGYYLGIYAMLGAVGMLSLIIGCWEMVINMVPKSGESFHRKLLATVLNAPMSFFAATDSGSILNRFSQDLQLIDMELPVAAINTFATLILCLAQMILMGIASRYAAISFPLVILAVYSIQKVYLRTSRQLRFLDLEAKAPLYSHFSDCLNGLVTLRAFGWQPALEDKNFQLLDYSQRPFYLLYAIQRWLTLTLDMVVAAIAVILIVLVVTLRGTISAGDVGVALLNVILFSQSIKLLVTFWTNLETHIGSIVRIRSFTETVSSENLPTEKDDVPPNWPWGGDIEFKSVSAEYRPSEPVLGDVSLTIKSGEKVGICGRTGSGKTSLIMSLFRMVELSSGSIHIDGVDITKIPRQEIRSRINGVSQSPLLIKGSIRRNMDPNGSYAEKAIIEAIKSVGLYTKIQEKGGLDTDISEVFLSQGQQQLFCLARAILRPGKVLVLDEATSNVDAKTDEIMQRVIREKFCTHTILAVAHKLETILDYDKVVVLDAGRVVESGDPCTLLSTEGSYFSRLYASSMALAEEQ