Protein
Acyl-protein thioesterase 1
Organism
Yarrowia lipolytica (strain CLIB 122 / E 150)
Function
Hydrolyzes fatty acids from S-acylated cysteine residues in proteins with a strong preference for palmitoylated G-alpha proteins over other acyl substrates.
Similarity
Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.
Sequence
MPPYPAVRIPAKAAHTATVIFLHGLGDSGAGWMFLAEEARKAQRLNHVKFIFPEAPQQPVSLNFGMRMPSWYDIKELANVNAAQDQEGILESVGRLESLIKEETDAGVPANRIVIGGFSQGCAVSLATGCLTQTKLGGIVGLSGYVPIKDYILSQHNTTNQDTPMFLAHGTADQVIRFDYGKLSRDFIINELKFKNVDWHQYEGLTHSCGFEEISDILNWLEENIKE