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Wnt6

Gene
WNT6
Protein
Protein Wnt-6
Organism
Homo sapiens
Length
365 amino acids
Function
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. Together with CAV1 may promote chemoresistance of gastric cancer cells to DNA-damaging anthracycline drugs through the activation of the canonical Wnt receptor signaling pathway.
Similarity
Belongs to the Wnt family.
Mass
39.721 kDa
Sequence
MLPPLPSRLGLLLLLLLCPAHVGGLWWAVGSPLVMDPTSICRKARRLAGRQAELCQAEPEVVAELARGARLGVRECQFQFRFRRWNCSSHSKAFGRILQQDIRETAFVFAITAAGASHAVTQACSMGELLQCGCQAPRGRAPPRPSGLPGTPGPPGPAGSPEGSAAWEWGGCGDDVDFGDEKSRLFMDARHKRGRGDIRALVQLHNNEAGRLAVRSHTRTECKCHGLSGSCALRTCWQKLPPFREVGARLLERFHGASRVMGTNDGKALLPAVRTLKPPGRADLLYAADSPDFCAPNRRTGSPGTRGRACNSSAPDLSGCDLLCCGRGHRQESVQLEENCLCRFHWCCVVQCHRCRVRKELSLCL

Gene
Wnt6
Protein
Protein Wnt-6
Organism
Mus musculus
Length
364 amino acids
Function
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters.
Similarity
Belongs to the Wnt family.
Mass
39.656 kDa
Sequence
MLPPVPSRLGLLLLLLCPAHVDGLWWAVGSPLVMDPTSICRKARRLAGRQAELCQAEPEVVAELARGARLGVRECQFQFRFRRWNCSSHSKAFGRVLQQDIRETAFVFAITAAGASHAVTQACSMGELLQCGCQAPRGRAPPRPSGLLGTPGPPGPTGSPDASAAWEWGGCGDDVDFGDEKSRLFMDAQHKRGRGDIRALVQLHNNEAGRLAVRSHTRTECKCHGLSGSCALRTCWQKLPPFREVGARLLERFHGASRVMGTNDGKALLPAVRTLKPPGRADLLYAADSPDFCAPNRRTGSPGTRGRACNSSAPDLSGCDLLCCGRGHRQESVQLEENCLCRFHWCCVVQCHRCRVRKELSLCL

Gene
wnt6
Protein
Protein Wnt-6
Organism
Xenopus laevis
Length
129 amino acids
Function
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters.
Similarity
Belongs to the Wnt family.
Mass
14.26 kDa
Fragment
single
Sequence
QECKCHGLSGSCTFTTCWKKMPHFREVGDRLLERFNGAFKVMGGNDGKTIIPVGHNIKPPDKQDLIYSAESPDFCQANRKTGSPGTRGRVCNSTALDVGGCDLLCCGRGQREETVVVEENCLCRFHWCC

Gene
wnt6
Protein
Protein Wnt-6
Organism
Thunnus thynnus
Length
117 amino acids
Function
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters.
Similarity
Belongs to the Wnt family.
Mass
13.064 kDa
Fragment
single
Sequence
SGSCTLRTCWKKMPHFREVGDRLLERFNGASKVMGGNDGKTLIPVGQNIKPPDKQDLIYSDESPDFCLANRKTGSLGTRGRMCNSTAMDISGCDLLCCERGYREESVVFEENCLCRF