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War-107

Gene
War-107
Protein
Repair DNA polymerase X
Organism
African swine fever virus (isolate Warthog/Namibia/Wart80/1980)
Length
174 amino acids
Function
Error-prone polymerase lacking a proofreading 3'-5' exonuclease which plays a role in viral DNA repair. Specifically binds intermediates in the single-nucleotide base-excision repair process. Also catalyzes DNA polymerization with low nucleotide-insertion fidelity. Together with the viral DNA ligase, fills the single nucleotide gaps generated by the AP endonuclease (By similarity).
Similarity
Belongs to the DNA polymerase type-X family.
Mass
20.335 kDa
Sequence
MLTLIQGKKIVNDLRSRLAFEYNGQLIKILSKNIVAVGSLRREEKMLNDVDLLIIVPEKKLLKHVLPNIRIKDFSFSIKVCGERKCVLFIEWKKNTYQLDLFTALAEEKPYAVLHFTGPVSYLIRIRAALKKKNYKLNQYGLFKNQTLVPLKITTEKELIKELGFTYRIPKKRL