WDR76

Gene

WDR76

Protein

WD repeat-containing protein 76

Organism

Rhinolophus ferrumequinum

Length

630 amino acids

Function

Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.

Similarity

Belongs to the WD repeat DDB2/WDR76 family.

Mass

70.085 kDa

Sequence

MSGSCAAAEEKEGSRQRLQMKVNEYKENQNMSSVSLRSIQKTVLEKTVKVCLVPFSLSNYKSGQFKLPKSLLDKNSKNEVACKKYKKTEIKKACTRILTSKMEATASSKAESTLQKSSIDVHTENNQRQHKSTSDTVSLGVDTESSQDGDSDEDTTSSLDDFSGLSPYERKRLKNISENANFFASLQLSESAARLREMIEKRQPPETKRKKPKKKENETGCRRSMRLLNVDPSGVSLPVTPTEPTLVADENPLLPPGPLEMIPENRDDNSELFKEFLQTWAEVSKTSSKNIEKELSSLKTYKANLSGMVISEDTVYKVTKGAIFSIAFHPSEIKTLVAAGAKSGQVGLWDLTHQPKEDGVYVFQPHSQPVSCLYFSPANPAHMLSLSYDGTLRCGDISSAVFEEVYRNERSSLSSFDFLAEDASTFIVGHWDGSISLVDRRTPGASYEKLISSSLRKIRTVHVHPVQRQYFITAGLRDTHIYDARRLTPSGSQPLISLTEHTKSIASAYFSPLTGNRIVTTCADCKLRFFDSSCISSQIPLLTTIRHNTITGRWLTRLRAVWDPKQEDCVIIGSMAHPRQVEIFHETGEQVHSFLGGECLVSVCSINAVHPTRYILAGGNSSGKIHVFMN

Protein

WD repeat-containing protein 76: WDR76

Gene

WDR76

Protein

WD repeat-containing protein 76

Organism

Homo sapiens

Length

626 amino acids

Function

Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.

Similarity

Belongs to the WD repeat DDB2/WDR76 family.

Mass

69.769 kDa

Sequence

MSRSGAAAEKADSRQRPQMKVNEYKENQNIAYVSLRPAQTTVLIKTAKVYLAPFSLSNYQLDQLMCPKSLSEKNSNNEVACKKTKIKKTCRRIIPPKMKNTSSKAESTLQNSSSAVHTESNKLQPKRTADAMNLSVDVESSQDGDSDEDTTPSLDFSGLSPYERKRLKNISENADFFASLQLSESAARLREMIEKRQPPKSKRKKPKRENGIGCRRSMRLLKVDPSGVSLPAAPTPPTLVADETPLLPPGPLEMTSENQEDNNERFKGFLHTWAGMSKPSSKNTEKGLSSIKSYKANLNGMVISEDTVYKVTTGPIFSMALHPSETRTLVAVGAKFGQVGLCDLTQQPKEDGVYVFHPHSQPVSCLYFSPANPAHILSLSYDGTLRCGDFSRAIFEEVYRNERSSFSSFDFLAEDASTLIVGHWDGNMSLVDRRTPGTSYEKLTSSSMGKIRTVHVHPVHRQYFITAGLRDTHIYDARRLNSRRSQPLISLTEHTKSIASAYFSPLTGNRVVTTCADCNLRIFDSSCISSKIPLLTTIRHNTFTGRWLTRFQAMWDPKQEDCVIVGSMAHPRRVEIFHETGKRVHSFGGEYLVSVCSINAMHPTRYILAGGNSSGKIHVFMNEKSC

Protein

WD repeat-containing protein 76: WDR76

Gene

WDR76

Protein

WD repeat-containing protein 76

Organism

Papio anubis

Length

626 amino acids

Function

Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.

Similarity

Belongs to the WD repeat DDB2/WDR76 family.

Mass

69.678 kDa

Sequence

MSRSGAAAEKADSRQRPQMKVNEYKENQNIAYVSLRPVQTTVLIKTAKVYLAPFSLSNYQLDQLMCPKSLLEKNSNNEVACKKTKIKKTCSRIIPPKMKTTSSKSESTLQNSASAVHTESNKLQPKRTADAMNLSVDVESSQDEDSDEDITPGLDDFSGLSPYERKRLKNISENADFFASLQLSESAARLREIIEKRQPPKSKRKKPKRENGVGCRRSMRLLKVDPSGVSLPATPTPPTLVADETPLLPPGPLEMTSENQEDNERFKGFLHTWAGMNKPSSKNTEKGLSSIKSYRANLNGMVISEDTVYKVTTGPIFSMALHPSETRTLVAVGAKFGQVGLCDLTQQPKEDGVYVFHPHSQPVSCLYFSPANPAHILSLSYDGTLRCGDFSRAIFEEVYRNERSSFSSFDFLSEDASTLIVGHWDGNMSLVDRRTPGTSYEKLTSSSMGKIRTVHVHPVHRQYFITAGLRDTHIYDARQLKSRGSQPLISLTEHTKSIASAYFSPLTGNRVVTTCADCNLRIFDSSCVSSKIPLLTTIRHNTFTGRWLTRFQAMWDPKQEDCVIVGSMAHPRRVEIFHETGKRVHSFGGECLVSVCSINAMHPTRYILAGGNSSGKIHVFMNEKSC

Protein

WD repeat-containing protein 76: WDR76

Gene

Wdr76

Protein

WD repeat-containing protein 76

Organism

Mus musculus

Length

622 amino acids

Function

Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.

Similarity

Belongs to the WD repeat DDB2/WDR76 family.

Mass

69.007 kDa

Sequence

MSGSKAESEEKAGSKQCPLVQVNEYKENEHIAYTSLRPIQITTLRKTAKVYLYPFSLSNSKLGLLKLSKSPVVNNSSKSVVHKKKDRKKTRRKVLTSKMKALSSKADSLLLKSSVDAYTESTRLGPKRTSDSATLSVDAESSDEDSAPGLDDFSGLSPYERKRLRNIRENANFFASLQLAESAARLRGMIKKRESPESKRKRPKKKENEIGCRRSMRLLKVDPLGVSLPASPTQPTLVEEEENPLLPPGPLEMIPENQDDSSELLKASLKTWAEMSQTSNEKTKKGLSSIKSYKANLSGMVISEATVRKVTKGAISSVALHPSEVRTLVAAGAKSGQIGLWDLTQQSEDAMYVFYAHSRYVSCLSFSPTNPAHLLSLSYDGTLRCGDFSSAVFEEVYRNEGNSPSSFDFLNDSSSLLVGHWDGHLSLVDRRTPGTSYEKFFNSSLEKIRTVHVHPLSRQYFVTAGLRDVHVYDARFLKSRGSQPLISLTEHSKSIASAYFSPVTGNRVVTTCADCKLRVFDSSSISSQLPLLSTIRHNTVTGRWLTRFQAVWDPKQEDCFIVGSMDHPRRVEVFHESGKNVHSLWGECLVSVCSLSAVHPTRYILAGGNSSGKLHVFMHQET

Protein

WD repeat-containing protein 76: Wdr76

Gene

wdr76

Protein

WD repeat-containing protein 76

Organism

Xenopus laevis

Length

580 amino acids

Function

Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.

Similarity

Belongs to the WD repeat DDB2/WDR76 family.

Mass

65.727 kDa

Sequence

MEEKKETAQMTQETTPKDSRVIEGVRRSSRRSHAEPHSPKKAYEVRDRRQKRSLERDQHEDGTPIKRARLPREQSSTRKHPIVLLSREIPEYHTETMPTPKKNYKLIPEQVTELSEYEIERLNNIKENAKFLQSLKLLETASSLRSPPKKQNQTRGIKREKQTKVERQPIIRRSMRLQRIDPSGAPLPNVIQPPEPLLEEHPVKPPGPLEMVPTNLKGDCISVEEFLKTWASTSKESLRSLKKQPSKDFKRYTACLQTMTLREETVAKVVQNRIFSVAIHPSESRTIVAAGDKWGQIGLWDLADLSGNDGVYVFEPHSRPISCMSFSPVNSAQLFSLSYDGTVRCGDVCRSVFDEVYRDEQDSFSSFDYLSADCSVLIVSHWDSYLSVVDCRTPGTSCEQRASLNMRSARTTSVHPVNRDLCVVAGAGDVCIFDVRQLKKKAQPVLSLTGHSKSVASAYFSPVTGNRILTTCADDYIRVYDSSSLCSEAPLLTAFRHNNNTGRWLTRFRAVWDPKQESCFVVGSMARPRQIEVYNESGKLEHSFWDSEHLGSVCSINAMHPTRNLLVGGNSSGRLHVFHD

Protein

WD repeat-containing protein 76: wdr76