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WASHC3

Gene
washc3
Protein
WASH complex subunit 3
Organism
Dictyostelium discoideum
Length
354 amino acids
Similarity
Belongs to the CCDC53 family.
Mass
38.411 kDa
Sequence
MQVYVDYRDVNSISNKKTLAYVNNFVINTTQFLNRFNYLCEQKLCDISNHLQKLEITMSLLEIKLGSIDGLESLPSSANVPVHNTQPTTQQNTPPPPTAAATTSSNIPPPPPPPPPPMTGVPPPPPPPPPPPISKSNIPPPPATQQNTQESDDDDEDNNNNDKNNNNRDDEDDDDETSSQAPPPPPMPTLPSSQSLMDNLAAVLAMKKQQRNPQPPQPQPQSPSPQPPPPPTTTSSIPVPPPPFSGANNNSDDDDDDDEGPSLSIPAPPSMMVMSGNNNSNSNSYSNNNNNKDDDDDDDDDDDDDDNSISIPKPPQMDDIMIPAPPTDLFIPAPPSIRNYDDADDDDDDDDESW

Gene
washc3
Protein
WASH complex subunit 3
Organism
Salmo salar
Length
210 amino acids
Similarity
Belongs to the CCDC53 family.
Mass
22.562 kDa
Sequence
MDEDGLPIVGSGIDLTKVPAIQQRRVVAYLNQFIVHTVRFLNRFSTVCEEKLASISLRIQQIETTLSILEAKLSSIPGLEDVRVEGVGQLPATEVNGPVTVVVPSQPETPIAVAVPLPPPEASPNIPDPRAAEAAGDGRMTVAKDPRYARYLKMVQVGVPVMAIKNKMVQEGLDPNLLDTPDAPVPDAVKKNTLDQDDDSDDGSESSFSD

Gene
washc3
Protein
WASH complex subunit 3
Organism
Danio rerio
Length
200 amino acids
Similarity
Belongs to the CCDC53 family.
Mass
21.565 kDa
Sequence
MDADGLPIVGSGVDLTKVPAIQQRRIVAFLNQFIVHTVRFLNRFSTVCEEKLSTVSLRIQQIETTLSILEAKLASIPGLEEVTVDGVRAPAETNGPAADTSRATAPPAEASQQTQAAPQEPKTEAPAENIMTVAKDPRYARYLKMVQVGVPVMAIKNKMMMEGLDPNLLDTPDAAVPDASKKRLEEQDDDSSGSESSFSD

Gene
washc3
Protein
WASH complex subunit 3
Organism
Xenopus laevis
Length
199 amino acids
Similarity
Belongs to the CCDC53 family.
Mass
21.684 kDa
Sequence
MDEDGLPIVGSGIDLTKVPPIQQKRTVAFLNQFVVHSVQFLNRFATVCEEKLSALSLRIQQIETTLNILEAKLSSIPGLEDVKVEAQHISESNISNGHLPSQPDAQSVVVSPQSDNNSMNDGILQKEEAKSENITTVSKDPRYARYLKMVQVGVPVMAIKNKMIAEGLNPDLLETPDAPVPDGEPEAEESSDSESSFSD

Gene
WASHC3
Protein
WASH complex subunit 3
Organism
Homo sapiens
Length
194 amino acids
Function
Acts at least in part as component of the WASH core complex whose assembly at the surface of endosomes seems to inhibit WASH nucleation-promoting factor (NPF) activity in recruiting and activating the Arp2/3 complex to induce actin polymerization, and which is involved in regulation of the fission of tubules that serve as transport intermediates during endosome sorting (PubMed:19922875, PubMed:20498093).
Similarity
Belongs to the CCDC53 family.
Mass
21.173 kDa
Sequence
MDEDGLPLMGSGIDLTKVPAIQQKRTVAFLNQFVVHTVQFLNRFSTVCEEKLADLSLRIQQIETTLNILDAKLSSIPGLDDVTVEVSPLNVTSVTNGAHPEATSEQPQQNSTQDSGLQESEVSAENILTVAKDPRYARYLKMVQVGVPVMAIRNKMISEGLDPDLLERPDAPVPDGESEKTVEESSDSESSFSD

Gene
Washc3
Protein
WASH complex subunit 3
Organism
Mus musculus
Length
194 amino acids
Function
Acts at least in part as component of the WASH core complex whose assembly at the surface of endosomes seems to inhibit WASH nucleation-promoting factor (NPF) activity in recruiting and activating the Arp2/3 complex to induce actin polymerization, and which is involved in regulation of the fission of tubules that serve as transport intermediates during endosome sorting.
Similarity
Belongs to the CCDC53 family.
Mass
21.093 kDa
Sequence
MDEDGLPLMGSGIDLTKVPAIQQKRTVAFLNQFVVHTVQFLNRFSAVCEEKLADLSLRIQQIETTLNILDAKLSSIPGLEDVTVEVSPLNVTAVTNGSHSETTSEQTQQNSTQDSGAQESEAPSENVLTVAKDPRYARYLKMVQVGVPVMAIRDKMISEGLDPELLEKPDAPVPNGESERAVEESSDSDSSFSD

Gene
WASHC3
Protein
WASH complex subunit 3
Organism
Bos taurus
Length
194 amino acids
Function
Acts at least in part as component of the WASH core complex whose assembly at the surface of endosomes seems to inhibit WASH nucleation-promoting factor (NPF) activity in recruiting and activating the Arp2/3 complex to induce actin polymerization, and which is involved in regulation of the fission of tubules that serve as transport intermediates during endosome sorting.
Similarity
Belongs to the CCDC53 family.
Mass
21.345 kDa
Sequence
MDEDGLPLMGSGIDLTKVPAIQQKRTVAFLNQFVVHTVQFLNRFSTVCEEKLADLSLRIQQIETTLNILDAKLSSIPGLDDVTFEVSPVNVTRITNGTHSEATSEQSQQNSLQDSGPQESEVTPENILTVAKDPRYARYHKMVQVGVPVMAIRNKMISEGLDPDLLERPDAPVPDGEGEKNTEESSDSESSFSD