Protein
Archaeal Lon protease
Organism
Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
Function
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Degrades polypeptides processively (By similarity).
Similarity
Belongs to the peptidase S16 family. Archaeal LonB subfamily.
Sequence
MSNESTNDAPPDDDPDDPEPSVDHDDTDGLQDDPADSVDDAGEVDDLENLGSDVGVEGDVSIDEDNAEDDLLGGLRIDDTSDITVPDRLVDQVIGQEAAREIVKRAAKQHRHVMMIGSPGTGKSLLAKAMSRLLPKESLQDVLVYHNPDDSNEPKVRTVPAGKGEQIVDAHKEEARKRNQMRSFLMWIMILLAVGYALLIATPARPLLALLSAAGIYLLFRYTNRGSDAMVPKLLINNADRQVAPFEDATGAHAGAMLGDVRHDPFQSGGMATPSHERVEAGSIQKANKGVLFIDEINTLDVRSQQKLMTAIQEGEFSITGQSERSSGAMVQTEAVPCDFIMVAAGNMDAMENMHPALRSRIKGYGYEVYMDDTIEDTPDMRRKYARFVAQEVEKDGNLPHFAPDAIRELILEAKRRAGRKDSLTLKLRDLGGLVRVAGDIARSEGHDLTQRSDVLEAKKRSRSIEQQFVDNYIQRRKDYELGTTSEEAVGRVNGLAVMGGDSGIMLPVMAEITPAQSQEEGRIYATGQLKEMAEEAVENVSAIIKKFSDENMSEKDTHIQFVQAGEGGVDGDSASITVATAVISALEDIPVAQELAMTGSLSVRGDVLPVGGVTHKIEAAAKAGCERVIIPKANEDDVMIEDEYEEQIEIIPVTHISEVLDVALVGEPEKDSLVDRLKSITGKALDSASDSGTTGGNPSPQ