Protein
Interferon antagonist C7
Organism
Vaccinia virus (strain Western Reserve)
Function
Inhibits antiviral activity induced by type I interferons. Does not block signal transdution of IFN, but is important to counteract the host antiviral state induced by a pre-treatment with IFN.
Similarity
Belongs to the poxviridae C7 protein family.
Sequence
MGIQHEFDIIINGDIALRNLQLHKGDNYGCKLKIISNDYKKLKFRFIIRPDWSEIDEVKGLTVFANNYAVKVNKVDDTFYYVIYEAVIHLYNKKTEILIYSDDENELFKHYYPYISLNMISKKYKVKEENYSSPYIEHPLIPYRDYESMD