UL27

Gene

UL27

Protein

Protein UL27

Organism

Human cytomegalovirus (strain AD169)

Length

608 amino acids

Function

Promotes a cell cycle arrest in G0/G1 by inducing the proteasomal degradation of host histone acetyltransferase KAT5/Tip60.

Similarity

Belongs to the herpesviridae U4 family.

Mass

69.22 kDa

Sequence

MNPVDQPPPPLPTQQPEEQAKEDHDDGDERLFRDPLTTYEYLDDCRDDEEFCHQFLRAYLTPIRNRQEAVRAGLLCRTPEDLAAAGGQKKKTPAPKHPKHAMVYIRRSCLVHSACATAHGKYDIRGLTLESDLAVWAALRGVPLPPDPQHFRWLNAGAFRRLVHEAQYLPEISRAAKRIALAVATGQYVVCTLLDYKTFGTRTHYLRQLCSMTEELYLRLDGTLCLFLEPEERELIGRCLPAALCRGLPVKYRTHRAAVFFHATFMARAEAALKDLYAAFCECGDGRDNGGNHDGNHDGNDHSSLSPSAVASHHSRLEHAELRLERNRHLGAFHLPAIRHLTAGDVARVQDSVSRDLGFADWSQTLIDDYFLLPAGWACANPRRGYAMYLASNAVLALRIIRLLRASIRHEYTACIRMLSGDVQRLIRLFKGEAALLRKGLAQNPVQRRELSRFRKHVHDLKRIRFTEDTFVETFCDFLELVQRIPDYRSVSLRIKRELLCLHVFKLRRGCRAPPTPETARVQRLLWHSLRHGDAPQDRTRLPQFSSALSDAELSNHANRCRRKAPLELGPAVVAAPGPSVRYRAHIQKFERLHVRRFRPHEVGGHAT

Protein

Protein UL27: UL27

Gene

UL27

Protein

Protein UL27

Organism

Human cytomegalovirus (strain Merlin)

Length

608 amino acids

Function

Promotes a cell cycle arrest in G0/G1 by inducing the proteasomal degradation of host histone acetyltransferase KAT5/Tip60.

Similarity

Belongs to the herpesviridae U4 family.

Mass

69.143 kDa

Sequence

MNPVDQPPPPPLTQQPEEQAKEDHDDGDERLFRDPLTTYEYLDDCRDDEEFCHQFLRAYLTPIRNRQEAVRAGLLCRTPEDLAAAGGQKRKTPAPKHPKHAMVYIRRSCLVHSACATAHGKYDIRGLTLESDLAVWAALRGVPLPPDPQHFRWLNAGAFRRLVHEAQYLPEISRAAKRIALAVATGQYVVCTLLDYKTFGTRTHYLRQLCSMTEELYLRLDGTLCLFLEPEERELIGRCLPAALCRGLPVKYRTHRAAVFFHATFMARAEAALKDLYAAFCECGDGRDDGGNHNGNYGGGDHSSLSPSAVASHHSRLEHAELRLERNRHLGAFHLPAIRHLTAGDVARVQDSVSRDLGFADWSQTLVDDYFLLPAGWACANPRRGYAMYLASNAVLALRIIRLLRASIRHEYTACIRMLSGDVQRLIRLFKGEAALLRKGLAQNPVQRRELSRFRKHVHDLKRIRFTEDTFVETFCDFLELVQRIPDYRSVSLRIKRELLCLHVFKLRRGCRAPPTPEAVRVQRLLWHSLRHGDAPQDRTRLPQFSSALSDAELSNHANRCRRKAPLELGPAVVAAPGPSVRYRAHIQKFERLHVRRFRPHEVGGHAT

Protein

Protein UL27: UL27