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UL2

Gene
UL2
Protein
Uracil-DNA glycosylase
Organism
Psittacid herpesvirus 1 (isolate Amazon parrot/-/97-0001/1997)
Length
362 amino acids
Function
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or deamination of cytosines. Therefore may reduce deleterious uracil incorporation into the viral genome, particularly in terminally differentiated cells which lack DNA repair enzymes.
Similarity
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
Mass
39.874 kDa
Sequence
MANDERVATGEDRAWGRLGVAELRIDAASVAPNDPTEDREVVLPIPGPAVSPIPRLTQPPRSSPPRPDAPSDLPRAQREPTKRSPATAGPTEDPNFADKIFKQAAPARKKPRFMPPPKLICGGVTDVTAELPAPSWDRVAEEFGIPDSWKNILAPLVETQRFAKTLQSYNGAKKSGNVLPSQDQIFAWARYCAPHEVKVIIVGQDPYPTEGDAHGLAFSVPVGRRVPPSLRRVFAALKDCYGDGFPTPSSGSLIAWAKQGVLLLNRHLTVERGLPRSHVSMGWDKLTFGVIKTLANDNPRMAVMLWGYDAKTFVPKLPSKHLRLEYSHPSTSTRRPFDCRHFIEANKFLEEGGLQAVVWRLP

Gene
UL2
Protein
Uracil-DNA glycosylase
Organism
Human herpesvirus 1 (strain 17)
Length
334 amino acids
Function
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or deamination of cytosines. Therefore may reduce deleterious uracil incorporation into the viral genome, particularly in terminally differentiated cells which lack DNA repair enzymes.
Similarity
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
Mass
36.328 kDa
Sequence
MKRACSRSPSPRRRPSSPRRTPPRDGTPPQKADADDPTPGASNDASTETRPGSGGEPAACRSSGPAALLAALEAGPAGVTFSSSAPPDPPMDLTNGGVSPAATSAPLDWTTFRRVFLIDDAWRPLMEPELANPLTAHLLAEYNRRCQTEEVLPPREDVFSWTRYCTPDEVRVVIIGQDPYHHPGQAHGLAFSVRANVPPPPSLRNVLAAVKNCYPEARMSGHGCLEKWARDGVLLLNTTLTVKRGAAASHSRIGWDRFVGGVIRRLAARRPGLVFMLWGTHAQNAIRPDPRVHCVLKFSHPSPLSKVPFGTCQHFLVANRYLETRSISPIDWSV

Gene
UL2
Protein
Uracil-DNA glycosylase
Organism
Suid herpesvirus 1 (strain Kaplan)
Length
316 amino acids
Function
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or deamination of cytosines. Therefore may reduce deleterious uracil incorporation into the viral genome, particularly in terminally differentiated cells which lack DNA repair enzymes.
Similarity
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
Mass
32.998 kDa
Sequence
MEGPPPSKRPCGLPPGVRLVVPAAAAASASNAATAAAAAAPAGAGAGASKPARPSAAARPAKGTPAASAATTATGADASAPPPDPGAPTWDAFAAEFDVAPSWRALLEPEIAKPYARLLLAEYRGRCLTEEVLPAREDVFAWTRLTAPEDVKVVIIGQDPYHGPGQAHGLAFSVRRGVPIPPSLANIFAAVRATYPTLPAPAHGCLEAWARRGVLLLNTTLTVRRGVPGSHAPLGWARLVRAVVQRLCETRPKLVFMLWGAHAQKACAPDPRRHKVLTFSHPSPLARTPFRTCPHFGEANAYLVQTGRAPVDWSVD

Gene
UL2
Protein
Uracil-DNA glycosylase
Organism
Suid herpesvirus 1 (strain Indiana-Funkhauser / Becker)
Length
315 amino acids
Function
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or deamination of cytosines. Therefore may reduce deleterious uracil incorporation into the viral genome, particularly in terminally differentiated cells which lack DNA repair enzymes.
Similarity
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
Mass
32.911 kDa
Sequence
MEGPPPSKRPCGLPPGVRLVVPAAAASASNAATAAAAAAPAGAGAGASKPARPPAAARPAKGTPAASAATTATGADASAPAPDPGAPTWDAFAAEFDVAPSWRALLEPEIAKPYARLLLAEYRGRCLTEEVLPAREDVFAWTRLTAPEDVKVVIIGQDPYHGPGQAHGLAFSVRRGVPIPPSLANIFAAVRATYPTLPAPAHGCLEAWARRGVLLLNTTLTVRRGVPGSHAPLGWARLVRAVVQRLCETRPKLVFMLWGAHAQKACAPDPRRHKVLTFSHPSPLARTPFRTCPHFGEANAYLVQTGRAPVDWSVD

Gene
UL2
Protein
Uracil-DNA glycosylase
Organism
Human herpesvirus 2 (strain 333)
Length
294 amino acids
Function
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or deamination of cytosines. Therefore may reduce deleterious uracil incorporation into the viral genome, particularly in terminally differentiated cells which lack DNA repair enzymes.
Similarity
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
Mass
32.495 kDa
Sequence
MAMKRNPSRVFCAYSKNGTHRSAAPTTHRCIAGGGRGALDAGAENTQGHPESRCFPGGRPPQTGPSWCLGAAFRRAFLIDDAWRPLLEPELANPLTARLLAEYDRRCQTEEVLPPREDVFSWTRYCTPDDVRVVIIGQDPYHHPGQAHGLAFSVRADVPVPPSLRNVLAAVKNCYPDARMSGRGCLEKWARDGVLLLNTTLTVKRGAAASTSKLGWDRFVGGVVRRLAARRPGLVFMLWGAHAQNAIRPDPRQHYVLKFSHPSPLSKVPFGTCQHFLAANRYLETRDIMPITVV

Gene
UL2
Protein
Uracil-DNA glycosylase
Organism
Human herpesvirus 2 (strain HG52)
Length
255 amino acids
Function
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or deamination of cytosines. Therefore may reduce deleterious uracil incorporation into the viral genome, particularly in terminally differentiated cells which lack DNA repair enzymes.
Similarity
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
Mass
28.48 kDa
Sequence
MFSASTTPEQPLGLSGDATPPLPTSVPLDWAAFRRAFLIDDAWRPLLEPELANPLTARLLAEYDRRCQTEEVLPPREDVFSWTRYCTPDDVRVVIIGQDPYHHPGQAHGLAFSVRADVPVPPSLRNVLAAVKNCYPDARMSGRGCLEKWARDGVLLLNTTLTVKRGAAASHSKLGWDRFVGGVVQRLAARRPGLVFMLWGAHAQNAIRPDPRQHYVLKFSHPSPLSKVPFGTCQHFLAANRYLETRDIMPIDWSV

Gene
UL2
Protein
Uracil-DNA glycosylase
Organism
Bovine herpesvirus 1.1 (strain Cooper)
Length
204 amino acids
Function
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or deamination of cytosines. Therefore may reduce deleterious uracil incorporation into the viral genome, particularly in terminally differentiated cells which lack DNA repair enzymes.
Similarity
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
Mass
22.421 kDa
Sequence
MPYTRHALREYERRSRVEQVLPPKADIFAWTRYAAPEDIKVVILGQDPYHSRGQAHGLAFSVNRGVPVPPSLQNIYAAVQKNFPGAPRPSHGCLEDWARRGVLLLNTSLTVRSGAPGSHSSLGWGRLVHAVLARLSAESGPLVFMLWGAHAQRAFGAAGKRHLVLTYSHPSPLSRAPFVHCTHFAEANAFLEQHGRGGVDWSIV

Gene
UL2
Protein
Uncharacterized protein UL2
Organism
Human cytomegalovirus (strain AD169)
Length
60 amino acids
Similarity
Belongs to the HHV-5 UL2 protein family.
Mass
6.762 kDa
Sequence
MAEDSVAILIVEDDNDAYPSFGTLPASHAQYGFRLLRGIFLITLVIWTVVWLKLLRDALL

Gene
UL2
Protein
Uncharacterized protein UL2
Organism
Human cytomegalovirus (strain Merlin)
Length
59 amino acids
Similarity
Belongs to the HHV-5 UL2 protein family.
Mass
6.696 kDa
Sequence
MAEDSVTILIVEDDDAYPSFGSLPASHAQYGFRLLRSIFLIMLVIWTAVWLKLLRDALL