Protein
Ubiquitin-like domain-containing CTD phosphatase 1
Organism
Xenopus tropicalis
Function
Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. The dephosphorylation may prevent assembly of the core and regulatory particles (CP and RP) into mature 26S proteasome (By similarity).
Sequence
MTLSLIIKWGGQEFPLSALSEEDTVLDLKHSLKSLTGVLPERMKLLGLKYKGKPAENDVKLGVLKLKPNTKIMMMGTREESLEEMMAPPPENDEVVNDFDIEEEVVEVENREENLAKISRRVKDYKIEILNPPREGKKLLVLDVDYTLFDHRSCAETGQELMRPYLHEFLTSAYEDYDIVIWSATSMKWIEAKMKELGVSTNSNYKITFMLDSAAMITVHTPRRGLVDVKPLGVIWGKYGEFYNKNNTIMFDDIGRNFLMNPQNGLKIRPFMKAHLNRDKDKELLKLSQYLKEIAQLDDLSELNHKHWERYLVKKQGQ