TUM1

Gene

TUM1

Protein

Thiosulfate sulfurtransferase TUM1

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

Length

304 amino acids

Function

Required for formation of the 2-thio group of the 5-methoxycarbonylmethyl-2-thiouridine modified base in some tRNAs.

Mass

34.219 kDa

Sequence

MPLFDLISPKAFVKLVASEKVHRIVPVDATWYLPSWKLDNKVDFLTKPRIPNSIFFDIDAISDKKSPYPHMFPTKKVFDDAMSNLGVQKDDILVVYDRVGNFSSPRCAWTLGVMGHPKVYLLNNFNQYREFKYPLDSSKVAAFSPYPKSHYESSESFQDKEIVDYEEMFQLVKSGELAKKFNAFDARSLGRFEGTEPEPRSDIPSGHIPGTQPLPYGSLLDPETKTYPEAGEAIHATLEKALKDFHCTLDPSKPTICSCGTGVSGVIIKTALELAGVPNVRLYDGSWTEWVLKSGPEWIAENRD

Protein

Thiosulfate sulfurtransferase TUM1: TUM1

Gene

tum1

Protein

Probable 3-mercaptopyruvate sulfurtransferase

Organism

Schizosaccharomyces pombe (strain 972 / ATCC 24843)

Length

298 amino acids

Function

Required for formation of the 2-thio group of the 5-methoxycarbonylmethyl-2-thiouridine modified base in some tRNAs.

Mass

32.8 kDa

Sequence

MFSVGKKISFILPIKGVLQKLKDNAQKTVLLDATWYLPTDTKNGKKEYLESRLPGAQYFDIDEAKDHKNPLPHMLPPADEFASYVGKLGIDRNTNVIIYDRKGFFSSPRVFWTFKVFGHEHVFLFPNAFNAWKTEGLELETGEPRTPKPVVYEGAKLNKDLVASFDDIVKVIESPDAAGVHIVDARAHERFLGNVPESRPGLASGHIPTSINIPFTETTAAGITAPKPEEDLEKVFSSHGLTDKSVPIITSCGSGVTASVLFAALKECGFKDVRVYDESWSGYGKRANEDSSLLATGP

Protein

Probable 3-mercaptopyruvate sulfurtransferase: tum1