Protein
Probable TtuB-protein conjugate cleaving protease
Organism
Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Function
Probable metalloprotease that cleaves the ubiquitin-like modifier protein TtuB from protein conjugates, hydrolyzing the isopeptide bond between a lysine residue of the target protein and the C-terminal glycine of the modifier protein. Does not seem to work for all the TtuB conjugates.
Similarity
Belongs to the peptidase M67B family.
Sequence
MAPPSVPIVYAGGRGGCPGGYHGLVLYVPRGLLEETRAHLLREAPKEGVGLWAGRREVERVIPLPNVHPSPLTAYLADPLALLKALKALEREGLSLLAIYHSHPKGPALPSPRDIKEARWRVPYVIFGTDGVRAFLLPEGQEVALVVL