Protein
Cystathionine beta-lyase
Organism
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Function
Catalyzes the transformation of cystathionine to homocysteine. Can also use cystine or S-methylcysteine as substrate.
Similarity
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. MalY/PatB cystathionine beta-lyase subfamily.
Sequence
MDLPPRTGSLKWGTYPEDVLPLWVADMDFPPAEAIQQALAERARGFLGYPPREGDRELRELILEALGLEAELAFMPGVVVGLYAAVAAFTAPGQGVLTQVPIYPPFLAAIRDQRRTVLANPLRETPEGYRLDLAGLERLAFATRLLLFCHPHNPTGRVFGEEELAALAQIARRHDLIVVSDELHAPLTYEKPHVPLARFLPERTLTLVGPGKTYNLAGLPIGAVLGPKPLVEAVKRHLPHVFPNVLAMAAWKAALKEGGPWLKATLEQLRANRDRVAAWAKARGLGHHPPEGTYLAWIQTPFPKAAAYFLERARVALNPGESFGRGYDTYVRLNFATYPEVLEEALRRLDGALK