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TSC10

Gene
TSC10
Protein
3-ketodihydrosphingosine reductase TSC10
Organism
Yarrowia lipolytica (strain CLIB 122 / E 150)
Length
372 amino acids
Function
Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Mass
40.734 kDa
Sequence
MIFPISEIPDKVTHSILEGVSALQNMSHTAFWSTVLGFLVVARIAVILATPKRRVLDIKGKKVVISGGSQGAGAALAELCYTKGANVVIVSRTVSKLEAQVQKIVTKHEPVFEGQTIRYISADLTKEEEAIRVFSEETMPAPPDVIFSCAGAAETGFILDFKASQLARAFSTNYLSALFFVHAGTTRMAKEPISPKNPRYVAIFSSVLAFYPLLGYGQYCASKAAVRSLIDSLRVEALPFNIRVVGVFPGNFQSEGFEEENKSKPEITRQIEGPSQAISAEECAKIVFAQMEKGGQMITTDLIGWILQSIALSSSPRSFSLLQIPLAIFMCIFSPVWNAFVNRDVRKYFHANTEYVTRHQRGGVGSENPTPQ
Protein
3-ketodihydrosphingosine reductase TSC10: TSC10

Gene
tsc10
Protein
3-ketodihydrosphingosine reductase tsc10
Organism
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
Length
369 amino acids
Function
Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Mass
40.461 kDa
Sequence
MHPSLPSIIYDASPTALGISAVFGALFFYTLVKMFGFLARENQFVVEGRTVVITGGSEGMGKAVACQLAQKGANIVIVARTLQKLEEAIEAIKGSAANVNKQRFHYISADLTKPEECERIMTEVTEWNDGMPPDIVWCCAGYCTPGYFVETSVQTLKDQMDTVYWTAANTAHAILRKWLVPINPSHQRPLPRRHLIFTCSTLAFVPIAGYAPYSPAKAAMRALSDTLCQEIEVYNGSRASKERARATPADVKIHTVFPMGILSPGFDNEQQIKPALTKQLESADKPQTPKEVARIAIEAIERGEYLITTMFVGDVMKGAALGPSPRNSWFRDTCTGWLSNLLFLGVVPDLRKQAFNWGAKNGVPTSPSA
Protein
3-ketodihydrosphingosine reductase tsc10: tsc10

Gene
TSC10
Protein
3-ketodihydrosphingosine reductase TSC10
Organism
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)
Length
363 amino acids
Function
Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Mass
40.41 kDa
Sequence
MFCLEDQVVLIAGGSQGLGKQFGQKYWDESRHSKIILVSRSDVKLRNAITDITGGRQEPVELVMPEVAASEPSASGSSAINLSKSSNHAGFESELRSNSNRSSSSLKESTNVVTHLTTNAADSRIVYIACDLSDPDAVERMFVTLQHNNLLPTQVLACAGGSIPKLFTDLTAKELEMGVKMNYMTTLFVIHKAAQMVPQAHLILFSSSTAFFPFIGYSQYAPAKVSLKALTSILRHELPNTRISCVYPGNFYSEGYVLEEMSKPDITKSIEGSSYPISCEECCDKIVWWLNRGYDDVTTDSIGWFLMSLDMGLNKHNNNSAYWFVQWLIGVIANLLVVPFYMVLCSYQINKWHKQNKNKNTLL
Protein
3-ketodihydrosphingosine reductase TSC10: TSC10

Gene
TSC10
Protein
3-ketodihydrosphingosine reductase TSC10
Organism
Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)
Length
335 amino acids
Function
Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Mass
36.504 kDa
Sequence
MPTPLALLLSAILIIGTYFAMPFWPFRKSNYDPRGKHCYITGGSSGLGKALAERLVKQGAHVTIVGRDSKKAEGVVEELKAIAAPGQIIQCIAADLTSPIASTNAIHAACKPHADQAPDYVYLCAGFSRPKLFVETTKQELKDGLDGVYWVSAYTAHEACQMMSKQRRTGKIIFVASFLSYVSFAGYSSYSPAKYALRGLSDALRSEMLLHNIDIHIFLPCGISGPGFDAENRTKPAVTKKIEEGDTPITPEVCAAALESGLKKGYYQITDNLVTEPIRLRSNGGVPTNNFLLDTLWLIVSSVGVPIWRMTADSAVRSFRAKVEKELEAKGYYVS
Protein
3-ketodihydrosphingosine reductase TSC10: TSC10

Gene
TSC10
Protein
3-ketodihydrosphingosine reductase TSC10
Organism
Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)
Length
335 amino acids
Function
Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Mass
36.49 kDa
Sequence
MPTPLALLLSAILIIGTYFAMPFWPFRKSNYDPRGKHCYITGGSSGLGKALAERLVKQGAHVTIVGRDSKKAEGVVEELKAIAAPGQIIQCIAADLTSPIASTNAIHAACKPHADQAPDYVYLCAGFSRPKLFVETTKQELKDGLDGVYWVSAYTAHEACQMMSKQRRTGKIIFVASFLSYVSFAGYSSYSPAKYALRGLSDALRSEMLLHNIDIHIFLPCGISGPGFDAENRTKPAVTKKIEEGDTPITPDVCAAALESGLKKGYYQITDNLVTEPIRLRSNGGVPTNNFLLDTLWLIVSSVGVPIWRMTADSAVRSFRAKVEKELEAKGYYVS
Protein
3-ketodihydrosphingosine reductase TSC10: TSC10

Gene
TSC10
Protein
3-ketodihydrosphingosine reductase TSC10
Organism
Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968)
Length
328 amino acids
Function
Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Mass
36.663 kDa
Sequence
MLFSNNKIHAEGKLALIVGASQGLGADLALKLYQQNCSVILVARTETKLVAQIERIQSSSPENNATLSYKCCDASNYEDCVKLWNDLIVDQKQDPDFIFCCAGSSIPKLFSDLTAKDFAIGINTNYTTSLNITHTGFKQVLGQFSDLSCDQYKKRHVIFVSSVVSFYPFIGYSQYAPLKSAIQSLSIILRQEMGPFNYRVSCVFPGNFQSEGYEEEQKTKPSITKSIEGSSKPISGEDCADIILNQLNRGYDTVTTDFIGWLLGCSVLGVLPRSWGFFQVIVSFIFSIIAPIANYVVYRDVLKFFKTRSTREVEEYEIVSTDDNKKTL
Protein
3-ketodihydrosphingosine reductase TSC10: TSC10

Gene
TSC10
Protein
3-ketodihydrosphingosine reductase TSC10
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
320 amino acids
Function
Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Mass
35.973 kDa
Sequence
MKFTLEDQVVLITGGSQGLGKEFAKKYYNEAENTKIIIVSRSEARLLDTCNEIRIEAHLRRETTDEGQVQHKLAAPLDLEQRLFYYPCDLSCYESVECLFNALRDLDLLPTQTLCCAGGAVPKLFRGLSGHELNLGMDINYKTTLNVAHQIALAEQTKEHHLIIFSSATALYPFVGYSQYAPAKAAIKSLVAILRQELTNFRISCVYPGNFESEGFTVEQLTKPEITKLIEGPSDAIPCKQACDIIAKSLARGDDDVFTDFVGWMIMGMDLGLTAKKSRFVPLQWIFGVLSNILVVPFYMVGCSWYIRKWFRENDGKKAN
Protein
3-ketodihydrosphingosine reductase TSC10: TSC10

Gene
TSC10
Protein
3-ketodihydrosphingosine reductase TSC10
Organism
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Length
313 amino acids
Function
Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Mass
34.859 kDa
Sequence
MKGFNCNGQVILISGGSQGLGESFAKRFVQDDDGPGSNTNKVIIVSRSQSKLVKACERIGVDGVSLDRYVNDTNRNETKLIYHSCDTSSYDKVALMFKLLVKSELVPSQVYMCAGGSIPKLFLDLTPEELQNGITTNYSTAVNLAHVSLKHDVPHLLFFSSEVAFFPFIGYAQYAPLKQSIRSLVAILRQEHSSTRITCVYPGNFQSEGFDLENITKPAITKEIEGPSNPVTAAQCRDKIISSLKWGLDDITTDSIGWLLMACDQGLNKHSTSQFMFVFSWILGALLNITIVPIYMLICKFQIYQWKRNKDTK
Protein
3-ketodihydrosphingosine reductase TSC10: TSC10

Gene
TSC10
Protein
3-ketodihydrosphingosine reductase TSC10
Organism
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
Length
307 amino acids
Function
Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Mass
32.76 kDa
Sequence
MKYELNGQVVLISGGSQGLGRAFAQKYIEESDSTVVIVSRSEEKLTRAGEAICGGARRLGAGGAGRLLYYACNLGDAAAVGGLFATLADAGLQVTQVLFCAGGAVPGLFAELSSAQLAAGVEMNYGTALHLAHGAVRHGARHLVFFSSAAAVYPFIGYSQYAPLKAALRALVAVLRQECDGVRVSCVYPGNFASEGYAEENRTKPAITAAIEGSSEAISCAACCDKIVRGLRSGYDDVTTDFVGWLLLACNMGFNYHSTTYFLWPLGWLLGALVNLLVVPIYMLLCRWDIHKWRTQREETHLAAKTD
Protein
3-ketodihydrosphingosine reductase TSC10: TSC10