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TOE1

Gene
TOE1
Protein
Target of EGR1 protein 1
Organism
Bos taurus
Length
524 amino acids
Function
Inhibits cell growth rate and cell cycle. Induces CDKN1A expression as well as TGF-beta expression. Mediates the inhibitory growth effect of EGR1. Involved in the maturation of snRNAs and snRNA 3'-tail processing.
Similarity
Belongs to the CAF1 family.
Mass
58.546 kDa
Sequence
MAADSDDGAASAPTVSDDGVRQSTKSGEELVVQVPVVDVQSDNFKEMWPSLLLAIKTANFVAVDTELSGLGDRKCLLNQCIEERYKAVCHAARTRSILSLGLACFKQQPDKGEHSYLAQVFNLTLLCMEEYVIEPKSVQFLVQHGFNFNRQYAQGIPYHKGNDKGDESQRQSVRTLFLELIRARRPLVLHNGLIDLVFLYQNFYAHLPENLGTFTADLCEMFPAGIYDTKYAAEFHARFLASYLEYAFRKCERENGKQRAAGSPHLTLEFCSYPSSMRAHIDYRCCAPPPTYRTHSTSICDNFSAYGWCPLGPQCPRSHDIDLIIDTDEAALEDKRRRRRRKEKRRRALLGLPGKQPSREAEDSPPTKQVCKDNRKPEETEQEVAEDETGTQPGSEQGHTNDLEMEPKATSAETTDTATSEAPERQVTTDMATSEAPERQVSPNPVPGDGLHRAGFDAFMTGYVMAYVGVSQGSHPCSSEPWLPECHNKVYLSGKAVPLTVVKSQFSRSSKAHNQKMKLAWGSS
Protein
Target of EGR1 protein 1: TOE1

Gene
Toe1
Protein
Target of EGR1 protein 1
Organism
Mus musculus
Length
511 amino acids
Function
Inhibits cell growth rate and cell cycle. Induces CDKN1A expression as well as TGF-beta expression. Mediates the inhibitory growth effect of EGR1. Involved in the maturation of snRNAs and snRNA 3'-tail processing.
Similarity
Belongs to the CAF1 family.
Mass
56.871 kDa
Sequence
MAADSDDDVPPVPTPSDGGVNKNTQPAEEFVVRVPVVDVQSDNFKEIWPSLLLALKTASFVAVDTELSGLGDRKSLLNQCIEERYKAVCHAARTRSVLSLGLACFRQQPDKGENSYLAQVFNLTLLCIEEYVIEPKSVQFLVQHGFNFNRQYAQGIPYHKGNDKGDESQSQSVRTLFLELIRARRPLVLHNGLIDLVFLYQNFYAHLPENLGTFTADLCEMFPAGIYDTKYAAEFHARFVASYLEYAFRKCERENGKQRAAGSPHLALEFCSYPSSMSGHIDYRCCMSPGTCRRSRTTGICDKFSAYGWCPLGPQCPQSHDIDLIIDTDEAVAEDKRRRRRRKDKRKRSLQSQPGTQTLAEAEDGPPTKQVCEDSLETEKMEQKVAEGEAGDQPGSREGHTSSLEMAHRRTSAETADVATSELLVNQASTNPVPGDGLHRAGFDAFMTGYVMAYVGLSQGLQLCSSEPWLPECHNKVYLSGKTVPLTVTKSQFSRPSKAHNQKMKLAWGSS
Protein
Target of EGR1 protein 1: Toe1

Gene
TOE1
Protein
Target of EGR1 protein 1
Organism
Homo sapiens
Length
510 amino acids
Function
Inhibits cell growth rate and cell cycle. Induces CDKN1A expression as well as TGF-beta expression. Mediates the inhibitory growth effect of EGR1. Involved in the maturation of snRNAs and snRNA 3'-tail processing (PubMed:28092684).
Similarity
Belongs to the CAF1 family.
Mass
56.548 kDa
Sequence
MAADSDDGAVSAPAASDGGVSKSTTSGEELVVQVPVVDVQSNNFKEMWPSLLLAIKTANFVAVDTELSGLGDRKSLLNQCIEERYKAVCHAARTRSILSLGLACFKRQPDKGEHSYLAQVFNLTLLCMEEYVIEPKSVQFLIQHGFNFNQQYAQGIPYHKGNDKGDESQSQSVRTLFLELIRARRPLVLHNGLIDLVFLYQNFYAHLPESLGTFTADLCEMFPAGIYDTKYAAEFHARFVASYLEYAFRKCERENGKQRAAGSPHLTLEFCNYPSSMRDHIDYRCCLPPATHRPHPTSICDNFSAYGWCPLGPQCPQSHDIDLIIDTDEAAAEDKRRRRRRREKRKRALLNLPGTQTSGEAKDGPPKKQVCGDSIKPEETEQEVAADETRNLPHSKQGNKNDLEMGIKAARPEIADRATSEVPGSQASPNPVPGDGLHRAGFDAFMTGYVMAYVEVSQGPQPCSSGPWLPECHNKVYLSGKAVPLTVAKSQFSRSSKAHNQKMKLTWGSS
Protein
Target of EGR1 protein 1: TOE1

Gene
TOE1
Protein
Target of EGR1 protein 1
Organism
Pongo abelii
Length
510 amino acids
Function
Inhibits cell growth rate and cell cycle. Induces CDKN1A expression as well as TGF-beta expression. Mediates the inhibitory growth effect of EGR1. Involved in the maturation of snRNAs and snRNA 3'-tail processing.
Similarity
Belongs to the CAF1 family.
Mass
56.482 kDa
Sequence
MAADSDDGAVPAPAASDGGVSKSTTSGEELVVQVPVVDVQSNNFREMWPSLLLAIKTANFVAVDTELSGLGDRKSLLNQCSEERYKAVCHAARTRSILSLGLACFKRQPDKGEHSYLAQVFNLTLLCMEEYVIEPKSVQFLIQHGFNFNQQYAQGIPYHKGNDKGDESQSQSVRTLFLELIRARRPLVLHNGLIDLVFLYQNFYAHLPESLGTFTADLCEMFPAGIYDTKYAAEFHARFVASYLEYAFRKCERENGKQRAAGSPHLTLEFCNYPSSMRDHIDYRCCLPPATHRPHPTSICDNFSAYGWCPLGPQCPQSHDIDLIIDTDEAAAEDKRRRRRRREKRKMALLNLPGTQTSGEAKDGPPKKQVCGDSLKAEETEQEVAEDETRNLPHSKQGNKNDLEMGIKAARPEIADTATSEVPGSQASPNPVPGDGLHRAGFDAFMTGYVMAYVEVSQGPQPCSSGPWLPECHNKVYLSGKAVPLTVAKSQFSRSSKAHNQKMKLAWGSS
Protein
Target of EGR1 protein 1: TOE1