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TMEM65

Gene
TMEM65
Protein
Transmembrane protein 65
Organism
Homo sapiens
Length
240 amino acids
Function
May play an important role in cardiac development and function. May regulate cardiac conduction and the function of the gap junction protein GJA1. May contributes to the stability and proper localization of GJA1 to cardiac intercalated disk thereby regulating gap junction communication (By similarity). May also play a role in the regulation of mitochondrial respiration and mitochondrial DNA copy number maintenance (PubMed:28295037).
Mass
25.498 kDa
Sequence
MSRLLPLLRSRTARSLRPGPAAAAAPRPPSWCCCGRGLLALAPPGGLPGGPRRLGTHPKKEPMEALNTAQGARDFIYSLHSTERSCLLKELHRFESIAIAQEKLEAPPPTPGQLRYVFIHNAIPFIGFGFLDNAIMIVAGTHIEMSIGIILGISTMAAAALGNLVSDLAGLGLAGYVEALASRLGLSIPDLTPKQVDMWQTRLSTHLGKAVGVTIGCILGMFPLIFFGGGEEDEKLETKS

Gene
TMEM65
Protein
Transmembrane protein 65
Organism
Bos taurus
Length
236 amino acids
Function
May play an important role in cardiac development and function. May regulate cardiac conduction and the function of the gap junction protein GJA1. May contributes to the stability and proper localization of GJA1 to cardiac intercalated disk thereby regulating gap junction communication (By similarity). Regulates mitochondrial respiration and mitochondrial DNA copy number maintenance (By similarity).
Mass
25.041 kDa
Sequence
MSRLLPLLRSRTARSLRPGPAAAAAPRPPSWCCCGRGLLALAAPGGPRALGTHPKKEPIEALNTAQGARDFIYSLHSSERSCLLKELHRFESIAIAQEKLEAQPPTPGQLRYVFIHNAIPFIGFGFLDNAIMIVAGTHIELSIGIILGISTMAAAALGNLVSDLAGLGLAGYVEALASRLGLSIPDLSPKQVDMWQTRVSSHLGKAVGVTIGCILGMFPLIFFGGGEDDEKLEKKN

Gene
Tmem65
Protein
Transmembrane protein 65
Organism
Mus musculus
Length
234 amino acids
Function
May play an important role in cardiac development and function. May regulate cardiac conduction and the function of the gap junction protein GJA1. May contributes to the stability and proper localization of GJA1 to cardiac intercalated disk thereby regulating gap junction communication (PubMed:26403541). Regulates mitochondrial respiration and mitochondrial DNA copy number maintenance (By similarity).
Mass
24.918 kDa
Sequence
MSRLLPLLGSRTARSLRPGPAAAPRLPSWCCCGRGLLALGVPGGPRLLGTHPKKEPMEALNTAQGARDFIYSLHSTERSCLLKELHRFESIAIAQEKLEALPPTPGQLRYVFFHNAIPFVGFGFLDNAIMIVAGTQIELSIGIILGISTMAAAALGNLVSDLAGLGLAGYVEALASRLGLSIPDLTPKQVDMWQTRVSTHLGKAVGVTIGCILGMFPLIFFGGSEEDEKLETTN

Gene
tmem65
Protein
Transmembrane protein 65
Organism
Danio rerio
Length
212 amino acids
Function
May play an important role in cardiac development and function. May regulate cardiac conduction and the function of the gap junction protein GJA1. May contributes to the stability and proper localization of GJA1 to cardiac intercalated disk thereby regulating gap junction communication (PubMed:26403541). Regulates mitochondrial respiration and mitochondrial DNA copy number maintenance (By similarity).
Mass
23.07 kDa
Sequence
MIRSVLLRALAARPPSAPVPGHLHRCLLGTHRRKIKPEQLELPNQTREFVYSLSPETRSRLLKELQTFESKTEDSGEASRLTAAQLRYILLHNAIPFIGFGFLDNAIMIAAGTQIELSIGLTLGISTMAAAALGNLVSDLAGLGLAGYVEALAVRLGMQIPDLSPRQVDMWQTRVSSHMGKAIGVAIGCILGMFPLLFLSDEEDKKPKKDSN