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TMEM170A

Gene
tmem170a
Protein
Transmembrane protein 170A
Organism
Danio rerio
Length
145 amino acids
Function
May regulate membrane morphogenesis in the endoplasmic reticulum (ER) by promoting ER sheet formation at the expense of ER tubules.
Similarity
Belongs to the TMEM170 family.
Mass
15.696 kDa
Sequence
MIEALIVGEMQDVQIGFVKQILSLNLVPRSNNTTCGNNTSLCDFSEMWYGVFLWAVVSSLIFHLPAALLALATLRRHKVARFFPLGILLMGIIGPLFGGVLTSAAIAGVYKAAGKSMFSLEALVFGVGQSLFIFIISFLRILATL

Gene
TMEM170A
Protein
Transmembrane protein 170A
Organism
Homo sapiens
Length
144 amino acids
Function
Acts as a regulator of endoplasmic reticulum (ER) and nuclear envelope (NE) morphogenesis. Affects the ratio between tubular ER and ER sheets by promoting sheet formation at the expense of tubules. Influences NE expansion, nuclear pore complex formation and proper localization of inner nuclear membrane proteins (PubMed:26906412).
Similarity
Belongs to the TMEM170 family.
Mass
15.25 kDa
Sequence
MEREGSGGSGGSAGLLQQILSLKVVPRVGNGTLCPNSTSLCSFPEMWYGVFLWALVSSLFFHVPAGLLALFTLRHHKYGRFMSVSILLMGIVGPITAGILTSAAIAGVYRAAGKEMIPFEALTLGTGQTFCVLVVSFLRILATL

Gene
Tmem170a
Protein
Transmembrane protein 170A
Organism
Mus musculus
Length
144 amino acids
Function
Acts as a regulator of endoplasmic reticulum (ER) and nuclear envelope (NE) morphogenesis. Affects the ratio between tubular ER and ER sheets by promoting sheet formation at the expense of tubules. Influences NE expansion, nuclear pore complex formation and proper localization of inner nuclear membrane proteins.
Similarity
Belongs to the TMEM170 family.
Mass
15.224 kDa
Sequence
MEREGSGGGGGSAGLLQQILSLKLVPRVGNGTLCPNSTSLCSFPEMWYGVFLWALMSSVFFHVPAGLLALFTLRHHKYGRFMSVSILLMGIVGPITAGILTSAAIAGVYRAAGKEMIPFEALTLGTGQTFCVVVVSFLRVLATL

Gene
tmem170a
Protein
Transmembrane protein 170A
Organism
Xenopus laevis
Length
142 amino acids
Function
May regulate membrane morphogenesis in the endoplasmic reticulum (ER) by promoting ER sheet formation at the expense of ER tubules.
Similarity
Belongs to the TMEM170 family.
Mass
15.128 kDa
Sequence
MEGGGGGLGGEPGLLQQILSLRLVPRVGNVTDCQRATLCSFPEMWYGVFLWALVSSLFFHIPAGLLALFTLRHHKYGRFMSVGIFLMGVLGPISAGILTSAAIAGVYKAAGKEMIPFEALVLGVGQTFCVLIVSFLRILATL

Gene
TMEM170A
Protein
Transmembrane protein 170A
Organism
Gallus gallus
Length
138 amino acids
Function
May regulate membrane morphogenesis in the endoplasmic reticulum (ER) by promoting ER sheet formation at the expense of ER tubules.
Similarity
Belongs to the TMEM170 family.
Mass
14.791 kDa
Sequence
MEGSEAGGGGLLQQILSLRLVPRVGNGTTYSSPLSTFPEMWYGVFLWALVSSLSFHVPAALLALFTLRHHKYGRFMSVSLLLMGIVGPITAGILTSAAIAGVYRAAGKKMIPFEALIFEVGQTFCVVVVSFLRILATL