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TKTL2

Gene
Tktl2
Protein
Transketolase-like protein 2
Organism
Mus musculus
Length
627 amino acids
Function
Plays an essential role in total transketolase activity and cell proliferation in cancer cells; after transfection with anti-TKTL1 siRNA, total transketolase activity dramatically decreases and proliferation was significantly inhibited in cancer cells. Plays a pivotal role in carcinogenesis (By similarity).
Similarity
Belongs to the transketolase family.
Mass
68.447 kDa
Sequence
MALARDAKLESDTLQVLQDVANRLRIHSIRATCACSSGHPTSCCSVAEIMAVLFFHTMRYKQADPEHPDNDRFVLSKGHAAPILYAVWVEVGRICESDLLNLRKIHCDLEGHPTPRLSFVDVATGSLGQGLGAACGMAYTGKYFDKASYRVFCLMGDGESSEGSVWEALAFASHYNLDNLVAIFDVNRLGQSGTAPLEHCTAVYEKRCQAFGWNTYVVDGHDVEALCQAFWKAAQVKNKPTALIAKTFKGRGIPNVEDAENWHGKPMPKDRADGIVKLIENRIQTNRNLTPKPPIEDSPRISMSNTKMTSLPVYKLGDMIATREAYGLALAKLGQSNQRVIVLDGDTKNSTFSEVFKKEHPERFIECFIAEQNMVSVALGCATRGRTIAFVSTFAAFLTRAFDQIRMGAISQTNINFVGSHCGVSVGEDGPSQMALEDLAMFRSIPNCTVFYPSDAVSTEHAVYLAANTKGMCFIRTTRPKTAVIYTAEENFVIGQAKVIRQSAVDKVTVIGAGVTLHEALVAAEELSQQGIFIRVIDLFTIKPLDAVTIIQSAKATGGQIITVEDHYREGGIGEAVCAAISREPDIVVRQLAVTEVPRSGKPSELLDMFGISARHIIAAVKDTVMK
Protein
Transketolase-like protein 2: Tktl2

Gene
TKTL2
Protein
Transketolase-like protein 2
Organism
Bos taurus
Length
626 amino acids
Function
Plays an essential role in total transketolase activity and cell proliferation in cancer cells; after transfection with anti-TKTL1 siRNA, total transketolase activity dramatically decreases and proliferation was significantly inhibited in cancer cells. Plays a pivotal role in carcinogenesis (By similarity).
Similarity
Belongs to the transketolase family.
Mass
67.501 kDa
Sequence
MADSATLDATTVQVLQDLANRLRVHSIRATCASGSGHPTSCCSAAEIVSVLFFHTMRYRQTEPAHPDNDRFVLSKGHAAPLLYAAWVEAGSISEPDLLNLRTIHCDLEGHPTPRLSFVDVATGSLGQGLGAACGMAYTGKYLDKASYRVFCLLGDGESSEGSVWEALAFASHYGLDNLVAVFDVNRLGQSGVAPLKHCTDIYRNRCEAFGWNTYLVDGHDVEALCQAFSQAAQGKNKPTAIIAKTYKGRGIPNVEDAENWHGKPLPKERADEIIRLIKSQIKTNRNLLPKPPVEGSPPVSITNIKMTCLPDYKVGDKVATQKAYGLALAKLGLANERVVVLDGDPKNSTFFEIFKKEHPERFIECFAAEQNMVSVALGCATRGRTITFVTTLGAFLTRAFDQIRMGAISQSNINLIGSHCGVSVGEDGPSQMALEDLAMFRSIPNCTVFLPSDAVSTEHAVYLAANSEGMCFIRTNRSETAVIYTPQEHFEIGRAKVIRHSNNDKVTVIGAGVTLHEALAAADALSQQDISICVIDPFTIKPLDAATIISCAKATDGRVVTVEDHYQEGGIGEAVCAAVSGEPAIHVHQLSVSGVSERNRKPSELLSIFGVSARHIIAAVKYTLMN
Protein
Transketolase-like protein 2: TKTL2

Gene
TKTL2
Protein
Transketolase-like protein 2
Organism
Homo sapiens
Length
626 amino acids
Function
Plays an essential role in total transketolase activity and cell proliferation in cancer cells; after transfection with anti-TKTL1 siRNA, total transketolase activity dramatically decreases and proliferation was significantly inhibited in cancer cells. Plays a pivotal role in carcinogenesis.
Similarity
Belongs to the transketolase family.
Mass
67.877 kDa
Sequence
MMANDAKPDVKTVQVLRDTANRLRIHSIRATCASGSGQLTSCCSAAEVVSVLFFHTMKYKQTDPEHPDNDRFILSRGHAAPILYAAWVEVGDISESDLLNLRKLHSDLERHPTPRLPFVDVATGSLGQGLGTACGMAYTGKYLDKASYRVFCLMGDGESSEGSVWEAFAFASHYNLDNLVAVFDVNRLGQSGPAPLEHGADIYQNCCEAFGWNTYLVDGHDVEALCQAFWQASQVKNKPTAIVAKTFKGRGIPNIEDAENWHGKPVPKERADAIVKLIESQIQTNENLIPKSPVEDSPQISITDIKMTSPPAYKVGDKIATQKTYGLALAKLGRANERVIVLSGDTMNSTFSEIFRKEHPERFIECIIAEQNMVSVALGCATRGRTIAFAGAFAAFFTRAFDQLRMGAISQANINLIGSHCGVSTGEDGVSQMALEDLAMFRSIPNCTVFYPSDAISTEHAIYLAANTKGMCFIRTSQPETAVIYTPQENFEIGQAKVVRHGVNDKVTVIGAGVTLHEALEAADHLSQQGISVRVIDPFTIKPLDAATIISSAKATGGRVITVEDHYREGGIGEAVCAAVSREPDILVHQLAVSGVPQRGKTSELLDMFGISTRHIIAAVTLTLMK
Protein
Transketolase-like protein 2: TKTL2