Protein
Digeranylgeranylglyceryl phosphate synthase
Organism
Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
Function
Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the UbiA prenyltransferase family. DGGGP synthase subfamily.
Sequence
MEFKAFIEITRPHNCLLAGIVGVLGSIVAAGGLPELKTAILVFLVVFLGCAGGNTINDYFDYEIDKINRPERPLPRGAMSRKAALWYSVALFATGIVLAWFINIWDFLLAIVAYVTMFIYAWKLKPMPFIGNVVVASLTGATPLYGAIAVGEIGLAGTLALCAFLVNVAREVIKDIEDIEGDMAKGAKTLPILIGRKRAAYVGALFAILTVVASFLPIKAGIGLGYLAMLPVDAVILYSAFLILRSQDRETAHRAQILLKVSVFLAVVAFLIASLVR