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TK0361

Gene
TK0361
Protein
Protein archease
Organism
Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
Length
142 amino acids
Function
Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently (By similarity).
Similarity
Belongs to the archease family.
Mass
16.41 kDa
Sequence
MRKWEHYEHTADIGVRGYGSTLEEAFEAVALGLFDVMVNVKKVEPKECREVEVEEEDLEALLYSFLEELLVLHDMEGLVFGDVKVRIEKTENGYKLKAKACGEVLNPEKHEPKEEVKAITYHDMKIEKLPDGRWMAQFVPDL